SCHEMBL24212569

SCHEMBL24212569

COC(=O)c1sc(C(F)(F)C(F)(F)F)cc1O

nearest known ligand 0.39

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
RAF1 P04049 11/20 0.39
MAPK14 Q16539 6/20 0.39
MAPT P10636 4/20 0.38
KMT2A Q03164 2/20 0.38
TSHR P16473 1/20 0.38
HSD17B10 Q99714 1/20 0.38
MAPK13 O15264 1/20 0.37
MAPK12 P53778 1/20 0.37
MAPK11 Q15759 1/20 0.37
PKM P14618 1/20 0.37
KDM4E B2RXH2 3/20 0.37
L3MBTL1 Q9Y468 2/20 0.37
LMNA P02545 1/20 0.37
POLB P06746 1/20 0.37
GAA P10253 1/20 0.37
NFKB1 P19838 1/20 0.37
XDH P47989 1/20 0.37
GFER P55789 1/20 0.37
NFKB2 Q00653 1/20 0.37
RELA Q04206 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL281723 0.87 RAF1 (0.42) RAF1MAPK14MAPTKMT2ATSHR
SCHEMBL24212568 0.84 RAF1 (0.40) RAF1MAPK14MAPTKMT2ATSHR
SCHEMBL24212638 0.79 MAPT (0.44) RAF1MAPK14MAPTKMT2ATSHR
SCHEMBL29360602 0.74 CFTR (0.39) MAPTKMT2ATSHRHSD17B10PKM
SCHEMBL29358940 0.73 SOS1 (0.40) MAPTKMT2ATSHRHSD17B10PKM
SCHEMBL9529269 0.72 TSHR (0.45) MAPTKMT2ATSHRHSD17B10KDM4E
SCHEMBL577650 0.72 MAPT (0.45) RAF1MAPK14MAPTKMT2ATSHR
SCHEMBL7670938 0.72 TSHR (0.45) MAPTKMT2ATSHRHSD17B10KDM4E
SCHEMBL577651 0.70 MAPT (0.44) RAF1MAPK14MAPTKMT2ATSHR
SCHEMBL11522285 0.70 MAPT (0.49) MAPTKMT2ATSHRHSD17B10KDM4E

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2022013417-A1 PESTICIDALLY ACTIVE HETEROCYCLIC DERIVATIVES WITH SULFUR CONTAINING SUBSTITUENTS SYNGENTA CROP PROTECTION AG (CH) 2022-01-20 WO disclosed