Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SOS1 | Q07889 | 1/20 | 0.40 |
| ▸ | NOTUM | Q6P988 | 2/20 | 0.39 |
| ▸ | PTPN2 | P17706 | 1/20 | 0.39 |
| ▸ | CFTR | P13569 | 2/20 | 0.38 |
| ▸ | GAA | P10253 | 4/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.33 |
| ▸ | MAPT | P10636 | 3/20 | 0.33 |
| ▸ | HPGD | P15428 | 3/20 | 0.33 |
| ▸ | CA12 | O43570 | 2/20 | 0.33 |
| ▸ | CA1 | P00915 | 2/20 | 0.33 |
| ▸ | CA2 | P00918 | 2/20 | 0.33 |
| ▸ | CA7 | P43166 | 2/20 | 0.33 |
| ▸ | CA9 | Q16790 | 2/20 | 0.33 |
| ▸ | CA14 | Q9ULX7 | 2/20 | 0.33 |
| ▸ | PDK2 | Q15119 | 2/20 | 0.33 |
| ▸ | PDK4 | Q16654 | 2/20 | 0.33 |
| ▸ | NR4A2 | P43354 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29361246 | 0.84 | PTPN2 (0.43) | PTPN2GAAALDH1A1MAPTHPGD | |
| SCHEMBL29360602 | 0.83 | CFTR (0.39) | SOS1NOTUMCFTRGAAALDH1A1 | |
| SCHEMBL29360699 | 0.81 | CFTR (0.35) | SOS1NOTUMPTPN2CFTRGAA | |
| SCHEMBL21054378 | 0.74 | CA12 (0.40) | SOS1CFTRGAAALDH1A1MAPT | |
| SCHEMBL24212568 | 0.73 | RAF1 (0.40) | ALDH1A1MAPTKMT2AHSD17B10NPC1 | |
| SCHEMBL24212569 | 0.73 | RAF1 (0.39) | GAAMAPTMEN1KMT2AHSD17B10 | |
| SCHEMBL17398205 | 0.73 | SMN1; SMN2 (0.47) | GAAALDH1A1MAPTHPGDCA12 | |
| SCHEMBL24212638 | 0.72 | MAPT (0.44) | NOTUMMAPTKMT2AHSD17B10NPC1 | |
| SCHEMBL5730997 | 0.69 | ALDH1A1 (0.56) | GAAALDH1A1MAPTHPGDMEN1 | |
| SCHEMBL17678398 | 0.69 | CA12 (0.36) | SOS1CFTRGAAALDH1A1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022017975-A1 | PESTICIDALLY ACTIVE HETEROCYCLIC DERIVATIVES WITH SULFUR CONTAINING SUBSTITUENTS | SYNGENTA CROP PROTECTION AG (CH) | 2022-01-27 | — | — | WO | disclosed |