Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 3/20 | 0.44 |
| ▸ | PKM | P14618 | 1/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.44 |
| ▸ | RAF1 | P04049 | 11/20 | 0.36 |
| ▸ | MAPK14 | Q16539 | 7/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | NPC1 | O15118 | 1/20 | 0.35 |
| ▸ | CASP3 | P42574 | 1/20 | 0.35 |
| ▸ | RAB9A | P51151 | 1/20 | 0.35 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.35 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.35 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.35 |
| ▸ | IKBKB | O14920 | 1/20 | 0.35 |
| ▸ | MAPK13 | O15264 | 1/20 | 0.34 |
| ▸ | MAPK12 | P53778 | 1/20 | 0.34 |
| ▸ | MAPK11 | Q15759 | 1/20 | 0.34 |
| ▸ | TSHR | P16473 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.34 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24212419 | 0.88 | L3MBTL1 (0.46) | MAPTPKML3MBTL1RAF1MAPK14 | |
| SCHEMBL161941 | 0.84 | L3MBTL1 (0.60) | MAPTPKML3MBTL1RAF1MAPK14 | |
| SCHEMBL24212569 | 0.79 | RAF1 (0.39) | MAPTPKML3MBTL1RAF1MAPK14 | |
| SCHEMBL24212568 | 0.79 | RAF1 (0.40) | MAPTPKML3MBTL1RAF1MAPK14 | |
| SCHEMBL21152318 | 0.77 | IKBKB (0.42) | MAPTPKML3MBTL1RAF1MAPK14 | |
| SCHEMBL29360699 | 0.77 | CFTR (0.35) | MAPTPKML3MBTL1RAF1MAPK14 | |
| SCHEMBL2729001 | 0.75 | GSK3B (0.43) | MAPTPKML3MBTL1RAF1KDM4E | |
| SCHEMBL14390861 | 0.75 | RAF1 (0.43) | MAPTL3MBTL1RAF1KDM4ENPC1 | |
| SCHEMBL13545972 | 0.74 | RAF1 (0.39) | MAPTPKML3MBTL1RAF1KDM4E | |
| SCHEMBL27928358 | 0.72 | L3MBTL1 (0.57) | MAPTPKML3MBTL1RAF1MAPK14 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022013417-A1 | PESTICIDALLY ACTIVE HETEROCYCLIC DERIVATIVES WITH SULFUR CONTAINING SUBSTITUENTS | SYNGENTA CROP PROTECTION AG (CH) | 2022-01-20 | — | — | WO | disclosed |