SCHEMBL24217754

SCHEMBL24217754

C=C/C=c1/cccc(CC)/c1=C/C=C

nearest known ligand 0.39

Predicted protein targets (top 3)

geneUniProtsupporting neighboursconfidence
GABRA1 P14867 4/20 0.39
GABRB2 P47870 4/20 0.39
CLCN2 P51788 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL22624872 0.70 CYP3A4 (0.33)
SCHEMBL11667899 0.69 ALDH1A1 (0.35)
SCHEMBL1363486 0.68 GABRA1 (0.50) GABRA1GABRB2
SCHEMBL18499741 0.66 ALDH1A1 (0.38)
SCHEMBL10077289 0.65 CD44 (0.30)
Propene SCHEMBL27662890 0.65 GABRA1 (0.46) GABRA1GABRB2
SCHEMBL6285101 0.63 GABRA1 (0.44) GABRA1GABRB2
SCHEMBL12802109 0.63 GABRA1 (0.45) GABRA1GABRB2
SCHEMBL198837 0.62 GABRA1 (0.55) GABRA1GABRB2CLCN2
SCHEMBL8346103 0.61 CD44 (0.30)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3943500-A1 PHOSPHOROUS PROTECTING GROUPS AND METHODS OF PREPARATION AND USE THEREOF Agilent Technologies, Inc. (US) 2022-01-26 EP disclosed