Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ESR1 | P03372 | 1/20 | 0.44 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.44 |
| ▸ | NR1H2 | P55055 | 2/20 | 0.35 |
| ▸ | NR1H3 | Q13133 | 2/20 | 0.35 |
| ▸ | TSHR | P16473 | 3/20 | 0.35 |
| ▸ | ACHE | P22303 | 2/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | NPC1 | O15118 | 3/20 | 0.32 |
| ▸ | RAB9A | P51151 | 3/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | GAA | P10253 | 1/20 | 0.31 |
| ▸ | CES2 | O00748 | 1/20 | 0.31 |
| ▸ | CES1 | P23141 | 1/20 | 0.31 |
| ▸ | TP53 | P04637 | 1/20 | 0.30 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.30 |
| ▸ | CA4 | P22748 | 1/20 | 0.30 |
| ▸ | BRD4 | O60885 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2169977 | 0.87 | ESR1 (0.48) | ESR1ESR2NR1H2NR1H3TSHR | |
| SCHEMBL2171513 | 0.85 | ESR1 (0.35) | ESR1ESR2 | |
| SCHEMBL11023948 | 0.81 | ESR1 (0.44) | ESR1ESR2NR1H2NR1H3TSHR | |
| SCHEMBL14600059 | 0.80 | ESR1 (0.45) | ESR1ESR2TSHRACHELMNA | |
| SCHEMBL14666537 | 0.79 | ESR1 (0.42) | ESR1ESR2NR1H2NR1H3TSHR | |
| SCHEMBL10150936 | 0.79 | ESR1 (0.42) | ESR1ESR2NR1H2NR1H3TSHR | |
| SCHEMBL8416131 | 0.78 | ESR1 (0.38) | ESR1ESR2NR1H2NR1H3TSHR | |
| SCHEMBL10613820 | 0.77 | ESR1 (0.41) | ESR1ESR2NR1H2NR1H3TSHR | |
| SCHEMBL9138483 | 0.77 | ESR1 (0.41) | ESR1ESR2NR1H2NR1H3TSHR | |
| SCHEMBL8662412 | 0.75 | ESR1 (0.44) | ESR1ESR2NR1H2NR1H3TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 85 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114262342-B | Method for purifying phenyl silane | 郑州原理生物科技有限公司 | 2022-12-27 | — | — | CN | claimed |
| CN-114262342-A | Method for purifying phenylsilane | 郑州原理生物科技有限公司 | 2022-04-01 | — | — | CN | claimed |
| EP-2346815-B1 | METHOD FOR PRODUCING COMPOUNDS INCLUDING NITRILE FUNCTIONS | INVISTA Technologies S à r l (CH) | 2016-04-20 | — | — | EP | claimed |
| US-20160009638-A1 | PROCESS FOR PRODUCING COMPOUNDS COMPRISING NITRILE FUNCTIONS | INVISTA NORTH AMERICA S.A R.L. (US) | 2016-01-14 | — | — | US | claimed |
| US-9174207-B2 | Process for producing compounds comprising nitrile functions | INVISTA NORTH AMERICA S.A.R.L. (US) | 2015-11-03 | — | — | US | claimed |
| EP-2411372-A1 | PROCESS FOR PREPARING ANTIVIRAL COMPOUND | Abbott Laboratories (US) | 2012-02-01 | — | — | EP | claimed |
| US-20120004440-A1 | PROCESS FOR PRODUCING COMPOUNDS COMPRISING NITRILE FUNCTIONS | INVISTA NORTH AMERICA SARL | 2012-01-05 | — | — | US | claimed |
| US-20110288327-A1 | PROCESS FOR THE MANUFACTURE OF COMPOUNDS COMPRISING NITRILE FUNCTIONAL GROUPS | RHODIA OPERATIONS (FR) | 2011-11-24 | — | — | US | claimed |
| WO-2010111348-A1 | PROCESS FOR PREPARING ANTIVIRAL COMPOUND | ABBOTT LABORATORIES (US) | 2010-09-30 | — | — | WO | claimed |
| WO-2010086246-A1 | METHOD FOR PRODUCING COMPOUNDS INCLUDING NITRILE FUNCTIONS | RHODIA OPERATIONS (FR) | 2010-08-05 | — | — | WO | claimed |
| WO-2010046226-A1 | METHOD FOR PRODUCING COMPOUNDS INCLUDING NITRILE FUNCTIONS | RHODIA OPERATIONS (FR) | 2010-04-29 | — | — | WO | claimed |
| EP-0325248-B1 | A process for the chlorodephenylation of phenylsilanes | DOW CORNING (US) | 1994-06-15 | — | — | EP | claimed |
| US-4855471-A | Process for the chlorodephenylation of phenyldisilanes | DOW CORNING CORPORATION (US) | 1989-08-08 | — | — | US | claimed |
| EP-0325248-A2 | A process for the chlorodephenylation of phenylsilanes | DOW CORNING CORPORATION (US) | 1989-07-26 | — | — | EP | claimed |
| JP-2009889-A | — | — | None | — | — | JP | disclosed |
| CN-119684346-A | Preparation method of selective beta-silicon-based aryl acetic acid compound | 扬州大学 | 2025-03-25 | — | — | CN | disclosed |
| CN-113169299-B | Nonaqueous electrolyte secondary battery | 三菱化学株式会社 | 2024-07-02 | — | — | CN | disclosed |
| JP-H029889-A | PREPARATION OF ALKYLHALODISILANE | DOW CORNING CORP | 1990-01-12 | — | — | JP | disclosed |
| US-4855471-A | Process for the chlorodephenylation of phenyldisilanes | DOW CORNING CORPORATION (US) | 1989-08-08 | — | — | US | disclosed |
| EP-0325248-A2 | A process for the chlorodephenylation of phenylsilanes | DOW CORNING CORPORATION (US) | 1989-07-26 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110288327-A1 | PROCESS FOR THE MANUFACTURE OF COMPOUNDS COMPRISING NITRILE FUNCTIONAL GROUPS | NIT2, LPO, CNDP2 | ESR1 3743/4885ESR2 4293/4885NR1H2 3928/4885 |
| US-20160009638-A1 | PROCESS FOR PRODUCING COMPOUNDS COMPRISING NITRILE FUNCTIONS | NIT2, NANP, LPO | ESR1 3565/4885ESR2 4469/4885NR1H2 3653/4885 |
| US-20120004440-A1 | PROCESS FOR PRODUCING COMPOUNDS COMPRISING NITRILE FUNCTIONS | NANP, NIT2, LPO | ESR1 3287/4885ESR2 4353/4885NR1H2 3465/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.