Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 6/20 | 0.50 |
| ▸ | FABP4 | P15090 | 3/20 | 0.47 |
| ▸ | FABP5 | Q01469 | 3/20 | 0.47 |
| ▸ | FABP3 | P05413 | 1/20 | 0.47 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.47 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.44 |
| ▸ | POLB | P06746 | 1/20 | 0.44 |
| ▸ | HPGD | P15428 | 1/20 | 0.43 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.43 |
| ▸ | GLA | P06280 | 1/20 | 0.42 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
| ▸ | EGFR | P00533 | 1/20 | 0.40 |
| ▸ | RXRA | P19793 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6468879 | 0.75 | CYP1A2 (0.48) | KDM4EFABP4FABP5FABP3CYP2C19 | |
| SCHEMBL19901140 | 0.73 | GPR3 (0.43) | KDM4ECYP2C19ALDH1A1POLBHPGD | |
| SCHEMBL6468350 | 0.72 | GPR3 (0.41) | KDM4ECYP2C19ALDH1A1POLBHPGD | |
| SCHEMBL14215108 | 0.71 | CYP1A2 (0.48) | KDM4EFABP4FABP5FABP3CYP2C19 | |
| SCHEMBL19565815 | 0.70 | GPR3 (0.40) | KDM4ECYP2C19ALDH1A1POLBHPGD | |
| SCHEMBL2608424 | 0.69 | GPR3 (0.52) | KDM4ECYP2C19ALDH1A1POLBHPGD | |
| SCHEMBL29625463 | 0.69 | GPR3 (0.52) | KDM4ECYP2C19ALDH1A1POLBHPGD | |
| SCHEMBL22809971 | 0.69 | GPR3 (0.39) | KDM4ECYP2C19ALDH1A1POLBHPGD | |
| SCHEMBL21426092 | 0.69 | CYP1A2 (0.47) | KDM4EFABP4FABP5FABP3CYP2C19 | |
| SCHEMBL22894392 | 0.69 | PGR (0.44) | KDM4ECYP2C19ALDH1A1HPGDHSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11229624-B2 | FABP4 as a therapeutic target in skin diseases | TICURE LTD. (IL) | 2022-01-25 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11229624-B2 | FABP4 as a therapeutic target in skin diseases | FABP4, FABP2, FABP1 | KDM4E 1557/4885FABP4 1/4885FABP5 4/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.