Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KCNH2 | Q12809 | 4/20 | 0.53 |
| ▸ | GRM2 | Q14416 | 1/20 | 0.48 |
| ▸ | MEN1 | O00255 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.46 |
| ▸ | PTPN11 | Q06124 | 1/20 | 0.45 |
| ▸ | DRD2 | P14416 | 1/20 | 0.45 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.43 |
| ▸ | GLA | P06280 | 1/20 | 0.43 |
| ▸ | TSHR | P16473 | 1/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.43 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10722675 | 0.85 | KMT2A (0.56) | MEN1KMT2ADRD2KDM4EGLA | |
| SCHEMBL10723742 | 0.85 | KMT2A (0.56) | MEN1KMT2ADRD2KDM4EGLA | |
| SCHEMBL20887230 | 0.82 | LMNA (0.55) | KCNH2MEN1KMT2A | |
| SCHEMBL10722375 | 0.79 | KMT2A (0.58) | MEN1KMT2ADRD2KDM4EGLA | |
| Bromide SCHEMBL3329889 | 0.76 | LMNA (0.40) | GRM2MEN1KMT2AKDM4EGLA | |
| Bromide SCHEMBL3329401 | 0.76 | LMNA (0.40) | GRM2MEN1KMT2AKDM4EGLA | |
| SCHEMBL9018985 | 0.76 | SMN1; SMN2 (0.59) | KCNH2ADRB1KDM4ETSHRMAPK1 | |
| SCHEMBL20887227 | 0.76 | LMNA (0.57) | MEN1KMT2AKDM4EGLA | |
| SCHEMBL10722736 | 0.75 | FAAH (0.48) | KDM4EGLAHSD17B10 | |
| SCHEMBL7122564 | 0.75 | FAAH (0.48) | KDM4EGLAHSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3562824-B1 | OXAZOLE DERIVATIVES FOR USE IN THE TREATMENT OF CANCER | LIFEARC (GB) | 2022-01-26 | — | — | EP | disclosed |