Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 4/20 | 0.56 |
| ▸ | MEN1 | O00255 | 3/20 | 0.56 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.51 |
| ▸ | GLA | P06280 | 1/20 | 0.51 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.50 |
| ▸ | POLB | P06746 | 1/20 | 0.50 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.48 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.48 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.48 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.48 |
| ▸ | GAA | P10253 | 1/20 | 0.48 |
| ▸ | PKM | P14618 | 1/20 | 0.48 |
| ▸ | DRD2 | P14416 | 1/20 | 0.47 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10722675 | 1.00 | KMT2A (0.56) | KMT2AMEN1KDM4EGLAHSD17B10 | |
| SCHEMBL10722375 | 0.94 | KMT2A (0.58) | KMT2AMEN1KDM4EGLAHSD17B10 | |
| SCHEMBL28657720 | 0.88 | KDM4E (0.64) | KMT2AMEN1KDM4EGLAHSD17B10 | |
| SCHEMBL24220554 | 0.85 | KCNH2 (0.53) | KMT2AMEN1KDM4EGLAHSD17B10 | |
| SCHEMBL19634850 | 0.84 | KMT2A (0.64) | KMT2AMEN1KDM4EHSD17B10DRD2 | |
| SCHEMBL108570 | 0.83 | MEN1 (0.57) | KMT2AMEN1POLB | |
| SCHEMBL10723979 | 0.82 | PKM (0.70) | KMT2APOLBGAAPKM | |
| SCHEMBL10722736 | 0.80 | FAAH (0.48) | KDM4EGLAHSD17B10GAAPKM | |
| SCHEMBL10721831 | 0.80 | FAAH (0.48) | KDM4EGLAHSD17B10GAAPKM | |
| SCHEMBL7122564 | 0.80 | FAAH (0.48) | KDM4EGLAHSD17B10GAAPKM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4663641-A | LEUCO DYES; DECOLORIZING AGENTS, PIPERAZINE COMPOUND; AMIDES AND TERTIARY AMINES | RICOH COMPANY, LTD. (JP) | 1987-05-05 | — | — | US | disclosed |