SCHEMBL2422572

SCHEMBL2422572

C=CC(=O)CCOc1ccc(C2(c3ccc(OCCC(=O)C=C)cc3)c3ccccc3-c3ccccc32)cc1

nearest known ligand 0.42

Predicted protein targets (top 13)

geneUniProtsupporting neighboursconfidence
PDK2 Q15119 13/20 0.42
MEN1 O00255 2/20 0.40
KMT2A Q03164 2/20 0.40
THRB P10828 1/20 0.40
POLB P06746 1/20 0.40
KDM4E B2RXH2 1/20 0.40
LMNA P02545 1/20 0.40
MAPT P10636 1/20 0.40
OPRK1 P41145 1/20 0.40
SMN1; SMN2 Q16637 1/20 0.40
ALDH1A1 P00352 1/20 0.37
L3MBTL1 Q9Y468 1/20 0.37
MMP3 P08254 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL17111003 0.94 PDK2 (0.43) PDK2MEN1KMT2ATHRBPOLB
SCHEMBL21035169 0.87 THRB (0.52) PDK2MEN1KMT2ATHRBPOLB
SCHEMBL16425350 0.86 MEN1 (0.42) PDK2MEN1KMT2ATHRBPOLB
SCHEMBL17111012 0.85 FFAR1 (0.47) PDK2
SCHEMBL14066386 0.84 ESR1 (0.38) PDK2MEN1KMT2APOLBKDM4E
SCHEMBL40434 0.83 THRB (0.63) PDK2MEN1KMT2ATHRBPOLB
SCHEMBL21884673 0.83 THRB (0.63) PDK2MEN1KMT2ATHRBPOLB
SCHEMBL29368072 0.83 THRB (0.63) PDK2MEN1KMT2ATHRBPOLB
Acrylic Acid SCHEMBL29704185 0.83 GAA (0.47) PDK2MEN1KMT2ATHRBPOLB
SCHEMBL18327172 0.82 THRB (0.55) PDK2MEN1KMT2ATHRBPOLB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-112646185-B Modified polythiol with high refractive index and preparation method thereof 益丰新材料股份有限公司 2023-04-28 CN disclosed
CN-112646185-A Modified polythiol with high refractive index and preparation method thereof 山东益丰生化环保股份有限公司 2021-04-13 CN disclosed
US-9580524-B2 Vinylcyclopropane, monomer composition, polymer, polymer composition, and article DEXERIALS CORPORATION (JP) 2017-02-28 US disclosed
US-20170022302-A1 VINYLCYCLOPROPANE, MONOMER COMPOSITION, POLYMER, POLYMER COMPOSITION, AND ARTICLE DEXERIALS CORPORATION (JP) 2017-01-26 US disclosed
US-8383295-B2 Composition for holographic recording medium KYOEISHA CHEMICAL CO., LTD. (JP) 2013-02-26 US disclosed
US-8022126-B2 A cured acrylic polymer based on a high-refractive index (meth)acrylic diester-fluorene monomer having a refractive index of >1.55 and a nonfunctional fluorene compound; heat resistance, light resistance, and flexibility equivalent to silicone resins; radiation transparent; auto headlights; backlighting SONY CORPORATION (JP) 2011-09-20 US disclosed
US-20100128589-A1 COMPOSITION FOR HOLOGRAPHIC RECORDING MEDIUM KYOEISHA CHEMICAL CO., LTD. (JP) 2010-05-27 US disclosed
US-20080233417-A1 OPTICAL POLYMER MATERIAL AND OPTICAL COMPONENT SANYO ELECTRIC CO., LTD. (JP) 2008-09-25 US disclosed
EP-1923433-A2 Encapsulating resin composition and light-emitting device Sony Chemical & Information Device Corporation (JP) 2008-05-21 EP disclosed
US-20080114100-A1 Encapsulating resin composition and light-emitting device SONY CHEMICAL & INFORMATION DEVICE CORPORATION (JP) 2008-05-15 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20170022302-A1 VINYLCYCLOPROPANE, MONOMER COMPOSITION, POLYMER, POLYMER COMPOSITION, AND ARTICLE VMP1, MTHFD2, PIN1 PDK2 1877/4885MEN1 826/4885KMT2A 2424/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.