Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.50 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.50 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.50 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.50 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.50 |
| ▸ | TSHR | P16473 | 1/20 | 0.50 |
| ▸ | CETP | P11597 | 3/20 | 0.44 |
| ▸ | MAPT | P10636 | 1/20 | 0.44 |
| ▸ | HPGD | P15428 | 1/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.42 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.42 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20794169 | 0.85 | ALDH1A1 (0.52) | ALDH1A1MAPK1TDP1L3MBTL1CYP3A4 | |
| SCHEMBL12013715 | 0.81 | ALDH1A1 (0.51) | ALDH1A1MAPK1TDP1L3MBTL1CYP3A4 | |
| SCHEMBL23027283 | 0.79 | ALDH1A1 (0.58) | ALDH1A1MAPK1TDP1L3MBTL1CYP3A4 | |
| SCHEMBL14476880 | 0.77 | CCR6 (0.63) | ALDH1A1MAPK1TDP1L3MBTL1CYP3A4 | |
| SCHEMBL24127602 | 0.77 | LTA4H (0.55) | ALDH1A1MAPK1TDP1L3MBTL1CYP3A4 | |
| SCHEMBL9790736 | 0.76 | ALDH1A1 (0.69) | ALDH1A1MAPK1TDP1L3MBTL1CYP3A4 | |
| SCHEMBL9190944 | 0.75 | ALDH1A1 (0.59) | ALDH1A1MAPK1TDP1L3MBTL1CYP3A4 | |
| SCHEMBL16877176 | 0.75 | ALDH1A1 (0.55) | ALDH1A1MAPK1TDP1L3MBTL1CYP3A4 | |
| SCHEMBL2724661 | 0.75 | ALDH1A1 (0.53) | ALDH1A1MAPK1TDP1L3MBTL1CYP3A4 | |
| SCHEMBL9562211 | 0.75 | ALDH1A1 (0.63) | ALDH1A1MAPK1TDP1L3MBTL1CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11236051-B2 | Compounds and methods for the targeted degradation of androgen receptor | ARVINAS OPERATIONS, INC. (US) | 2022-02-01 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11236051-B2 | Compounds and methods for the targeted degradation of androgen receptor | AR, ADRM1, CRBN | ALDH1A1 798/4885MAPK1 4010/4885TDP1 2798/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.