Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MMP3 | P08254 | 6/20 | 0.48 |
| ▸ | MMP1 | P03956 | 5/20 | 0.48 |
| ▸ | MMP9 | P14780 | 1/20 | 0.48 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.47 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.47 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.47 |
| ▸ | LMNA | P02545 | 1/20 | 0.47 |
| ▸ | PKM | P14618 | 1/20 | 0.47 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.46 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.46 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.46 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.46 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.46 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.46 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.46 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.46 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.46 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25058925 | 1.00 | MMP3 (0.48) | MMP3MMP1MMP9CYP2D6CYP2C9 | |
| SCHEMBL24233258 | 1.00 | MMP3 (0.48) | MMP3MMP1MMP9CYP2D6CYP2C9 | |
| SCHEMBL13227756 | 0.90 | TSHR (0.51) | KMT2ASMN1; SMN2ALDH1A1HPGDTSHR | |
| SCHEMBL24233257 | 0.90 | TSHR (0.51) | KMT2ASMN1; SMN2ALDH1A1HPGDTSHR | |
| SCHEMBL16509240 | 0.90 | TSHR (0.51) | KMT2ASMN1; SMN2ALDH1A1HPGDTSHR | |
| SCHEMBL21837706 | 0.88 | GGT1 (0.52) | MMP3MMP1CYP2D6CYP2C9CYP2C19 | |
| SCHEMBL21837703 | 0.88 | GGT1 (0.52) | MMP3MMP1CYP2D6CYP2C9CYP2C19 | |
| SCHEMBL23875099 | 0.85 | KDM4E (0.47) | LMNASLC6A3ALDH1A1 | |
| SCHEMBL16329068 | 0.85 | GNPAT (0.51) | MMP3MMP1MMP9CYP2D6CYP2C9 | |
| SCHEMBL7997620 | 0.84 | MMP3 (0.52) | MMP3MMP1MMP9CYP2D6CYP2C9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022023723-A1 | GLP-1 RECEPTOR ANTAGONISTS | HEPTARES THERAPEUTICS LIMITED (GB) | 2022-02-03 | — | — | WO | disclosed |