Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MMP3 | P08254 | 5/20 | 0.52 |
| ▸ | GGT1 | P19440 | 1/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.46 |
| ▸ | MMP1 | P03956 | 3/20 | 0.45 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.45 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.45 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.45 |
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
| ▸ | PKM | P14618 | 1/20 | 0.44 |
| ▸ | MMP9 | P14780 | 1/20 | 0.44 |
| ▸ | EPHX2 | P34913 | 2/20 | 0.43 |
| ▸ | KDM4A | O75164 | 1/20 | 0.43 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.43 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.43 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.43 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.43 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.43 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29152262 | 0.89 | MMP3 (0.51) | MMP3GGT1SMN1; SMN2MMP1CYP2D6 | |
| SCHEMBL1755666 | 0.86 | MMP3 (0.54) | MMP3GGT1SMN1; SMN2CYP2D6CYP2C9 | |
| SCHEMBL24233258 | 0.84 | MMP3 (0.48) | MMP3SMN1; SMN2MMP1CYP2D6CYP2C9 | |
| SCHEMBL24233261 | 0.84 | MMP3 (0.48) | MMP3SMN1; SMN2MMP1CYP2D6CYP2C9 | |
| SCHEMBL25058925 | 0.84 | MMP3 (0.48) | MMP3SMN1; SMN2MMP1CYP2D6CYP2C9 | |
| SCHEMBL10889835 | 0.84 | MMP3 (0.49) | MMP3SMN1; SMN2LMNAHDAC3HDAC4 | |
| SCHEMBL16329068 | 0.83 | GNPAT (0.51) | MMP3SMN1; SMN2MMP1CYP2D6CYP2C9 | |
| SCHEMBL14027140 | 0.80 | SIGMAR1 (0.55) | PKMHDAC3HDAC4HDAC1HDAC2 | |
| SCHEMBL2208436 | 0.79 | MME (0.55) | GGT1SMN1; SMN2KMT2AHPGD | |
| SCHEMBL2208433 | 0.79 | MME (0.55) | GGT1SMN1; SMN2KMT2AHPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009125424-A2 | PEPTIDOMIMETICS WITH GLUCAGON ANTAGONISTIC AND GLP-1 AGONISTIC ACTIVITIES | CADILA HEALTHCARE LIMITED (IN) | 2009-10-15 | — | — | WO | disclosed |