Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NMT1 | P30419 | 4/20 | 0.38 |
| ▸ | NMT2 | O60551 | 3/20 | 0.38 |
| ▸ | KISS1R | Q969F8 | 1/20 | 0.36 |
| ▸ | NOD1 | Q9Y239 | 2/20 | 0.35 |
| ▸ | SIRT5 | Q9NXA8 | 2/20 | 0.35 |
| ▸ | TLR2 | O60603 | 1/20 | 0.34 |
| ▸ | FURIN | P09958 | 3/20 | 0.32 |
| ▸ | FOLH1 | Q04609 | 1/20 | 0.32 |
| ▸ | NPY1R | P25929 | 1/20 | 0.31 |
| ▸ | NPY2R | P49146 | 1/20 | 0.31 |
| ▸ | NPY4R | P50391 | 1/20 | 0.31 |
| ▸ | NPY5R | Q15761 | 1/20 | 0.31 |
| ▸ | GLP1R | P43220 | 3/20 | 0.31 |
| ▸ | SIRT6 | Q8N6T7 | 1/20 | 0.30 |
| ▸ | SIRT1 | Q96EB6 | 1/20 | 0.30 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24235488 | 0.91 | NMT1 (0.39) | NMT1NMT2KISS1RNOD1SIRT5 | |
| SCHEMBL23446572 | 0.83 | KISS1R (0.39) | NMT1NMT2KISS1RNOD1SIRT5 | |
| SCHEMBL23446658 | 0.79 | NOD1 (0.44) | KISS1RNOD1 | |
| SCHEMBL26166948 | 0.79 | TLR2 (0.41) | NMT1NMT2KISS1RNOD1SIRT5 | |
| SCHEMBL23447289 | 0.76 | NOD1 (0.46) | NMT1NMT2KISS1RNOD1TLR2 | |
| SCHEMBL26864918 | 0.75 | NMT1 (0.35) | NMT1NMT2KISS1RNOD1SIRT5 | |
| SCHEMBL26864763 | 0.75 | NMT1 (0.35) | NMT1NMT2KISS1RNOD1SIRT5 | |
| SCHEMBL23446084 | 0.75 | KISS1R (0.37) | NMT1NMT2KISS1RNOD1SIRT5 | |
| SCHEMBL15791248 | 0.75 | KISS1R (0.42) | NMT1NMT2KISS1RNOD1FURIN | |
| SCHEMBL27315235 | 0.75 | NMT2 (0.43) | NMT1NMT2NOD1SIRT5TLR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022022360-A1 | POLYETHYLENE GLYCOL CONJUGATE DRUG, AND PREPARATION METHOD THERFOR AND USE THEREOF | 重庆阿普格雷生物科技有限公司 | 2022-02-03 | — | — | WO | disclosed |