Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.50 |
| ▸ | NCF1 | P14598 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | NAMPT | P43490 | 1/20 | 0.40 |
| ▸ | CACNA1I | Q9P0X4 | 3/20 | 0.39 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.39 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.38 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.38 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.38 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.38 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.38 |
| ▸ | ADRA1D | P25100 | 1/20 | 0.38 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.38 |
| ▸ | ADRA1B | P35368 | 1/20 | 0.38 |
| ▸ | TPSAB1 | Q15661 | 1/20 | 0.38 |
| ▸ | TPSD1 | Q9BZJ3 | 1/20 | 0.38 |
| ▸ | TPSG1 | Q9NRR2 | 1/20 | 0.38 |
| ▸ | PARP1 | P09874 | 1/20 | 0.37 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.37 |
| ▸ | GSK3B | P49841 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13621194 | 0.84 | TDP1 (0.67) | TDP1NCF1MAPTNAMPTHDAC1 | |
| SCHEMBL12964152 | 0.82 | CKS1B (0.46) | TDP1NCF1MAPTNAMPTCACNA1I | |
| SCHEMBL21730472 | 0.79 | FAAH (0.46) | MAPTNAMPTHDAC1HDAC2HDAC4 | |
| SCHEMBL15224105 | 0.78 | TDP1 (0.57) | TDP1EPHX1 | |
| SCHEMBL8136269 | 0.78 | MTNR1A (0.45) | TDP1NCF1MAPTNAMPTHDAC4 | |
| SCHEMBL16494745 | 0.78 | CYP2D6 (0.50) | TDP1NCF1MAPTNAMPTHDAC1 | |
| SCHEMBL22519427 | 0.78 | SMN1; SMN2 (0.49) | TDP1NCF1MAPTNAMPTCACNA1I | |
| SCHEMBL23173065 | 0.77 | MAPT (0.43) | TDP1NCF1MAPTNAMPTHDAC1 | |
| SCHEMBL10205595 | 0.77 | NCF1 (0.47) | TDP1NCF1MAPTNAMPTHDAC1 | |
| SCHEMBL16111098 | 0.77 | NCF1 (0.47) | TDP1NCF1MAPTNAMPTHDAC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20220033436-A1 | DERIVATIVE OF SARSASAPOGENIN, PHARMACEUTICAL COMPOSITION AND USE THEREOF | PHYTOVENT BIOPHARMA (CN) | 2022-02-03 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20220033436-A1 | DERIVATIVE OF SARSASAPOGENIN, PHARMACEUTICAL COMPOSITION AND USE THEREOF | SARS1, ACE2, FURIN | TDP1 4026/4885NCF1 4435/4885MAPT 3550/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.