Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARG | P37231 | 2/20 | 0.38 |
| ▸ | PPARA | Q07869 | 2/20 | 0.38 |
| ▸ | NR1H4 | Q96RI1 | 1/20 | 0.34 |
| ▸ | BRD4 | O60885 | 1/20 | 0.33 |
| ▸ | BAZ2B | Q9UIF8 | 1/20 | 0.33 |
| ▸ | BAZ2A | Q9UIF9 | 1/20 | 0.33 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.32 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.32 |
| ▸ | MAPT | P10636 | 2/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.32 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.31 |
| ▸ | ATM | Q13315 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.31 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.30 |
| ▸ | GAA | P10253 | 1/20 | 0.30 |
| ▸ | THRB | P10828 | 1/20 | 0.30 |
| ▸ | HPGD | P15428 | 1/20 | 0.30 |
| ▸ | HTT | P42858 | 1/20 | 0.30 |
| ▸ | GFER | P55789 | 1/20 | 0.30 |
| ▸ | PLEC | Q15149 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24242591 | 0.86 | PPARA (0.42) | PPARGPPARABRD4BAZ2BBAZ2A | |
| SCHEMBL20953597 | 0.86 | PPARA (0.42) | PPARGPPARABRD4BAZ2BBAZ2A | |
| SCHEMBL13407994 | 0.82 | PPARG (0.39) | PPARGPPARANR1H4BRD4BAZ2B | |
| SCHEMBL13407996 | 0.82 | LMNA (0.35) | PPARGPPARANR1H4TRPA1MAPT | |
| SCHEMBL23490292 | 0.81 | MEN1 (0.38) | PPARGPPARABRD4BAZ2BBAZ2A | |
| SCHEMBL14252234 | 0.77 | POLB (0.37) | PPARGPPARABRD4BAZ2BBAZ2A | |
| SCHEMBL22549043 | 0.73 | NPSR1 (0.37) | PPARGPPARAL3MBTL1NPSR1ALDH1A1 | |
| SCHEMBL12518234 | 0.73 | ACHE (0.45) | L3MBTL1MAPTSMN1; SMN2NPSR1ATM | |
| SCHEMBL8721308 | 0.72 | PPARG (0.36) | PPARGPPARAL3MBTL1NPSR1 | |
| SCHEMBL11382828 | 0.72 | MAPT (0.50) | PPARGPPARABRD4BAZ2BBAZ2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20220031847-A1 | THERAPEUTIC METHODS | GENEVANT SCIENCES GMBH (CH) | 2022-02-03 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20220031847-A1 | THERAPEUTIC METHODS | NUP205, HNRNPH3, FUS | PPARG 3753/4885PPARA 2954/4885NR1H4 445/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.