Dioxaphetyl Butyrate

Dioxaphetyl Butyrate

SCHEMBL24240

CCOC(=O)C(CCN1CCOCC1)(c1ccccc1)c1ccccc1

nearest known ligand 0.73

Full drug profile on Sugi Atlas →

Predicted protein targets (top 12)

geneUniProtsupporting neighboursconfidence
OPRM1 P35372 4/20 0.73
OPRD1 P41143 1/20 0.73
KMT2A Q03164 5/20 0.50
MEN1 O00255 3/20 0.50
LMNA P02545 3/20 0.49
OPRL1 P41146 2/20 0.47
ALDH1A1 P00352 7/20 0.46
CYP2C19 P33261 1/20 0.46
KDM4E B2RXH2 1/20 0.46
GAA P10253 1/20 0.46
HPGD P15428 1/20 0.46
MAPT P10636 3/20 0.46

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10558801 0.80 OPRM1 (0.51) OPRM1OPRD1KMT2AMEN1LMNA
SCHEMBL16079213 0.78 OPRM1 (0.51) OPRM1OPRD1KMT2AMEN1LMNA
Desmethylmoramide SCHEMBL2111155 0.77 OPRM1 (0.68) OPRM1OPRD1KMT2AMEN1LMNA
SCHEMBL8592701 0.76 SCN1A (0.67) OPRM1OPRD1KMT2AMEN1LMNA
SCHEMBL29439076 0.76 LMNA (0.62) OPRM1OPRD1KMT2ALMNAALDH1A1
SCHEMBL12463688 0.76 SMN1; SMN2 (0.49) OPRM1OPRD1KMT2AMEN1LMNA
SCHEMBL30046972 0.74 LMNA (0.54) OPRM1OPRD1LMNAALDH1A1KDM4E
SCHEMBL28047418 0.74 SCN1A (0.56) OPRM1KMT2AMEN1LMNAALDH1A1
SCHEMBL28970082 0.73 CHRM2 (0.65) OPRM1OPRD1KMT2AMEN1LMNA
SCHEMBL11601137 0.72 OPRM1 (0.60) OPRM1OPRD1KMT2AMEN1LMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Appears in 5515 patents — a generic fragment claimed broadly, so it's down-weighted as IP noise. Top by claim status then date:

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4724049-A1 MODIFIED RELEASE FILL COMPOSITIONS FOR DOSAGE FORMS AND METHODS OF PREPARATION AND USE THEREOF Catalent Ontario Limited (CA) 2026-04-15 EP claimed
US-20250319074-A1 TREATMENT AND MANAGEMENT OF AUGMENTATION IN RESTLESS LEGS SYNDROME UNIV EAST CAROLINA (US) 2025-10-16 US claimed
US-12383743-B2 Treatment of addiction and dependency TACA JR ARTURO C (US) 2025-08-12 US claimed
US-20250228771-A1 ALKALINE INTRAORAL PRODUCTS EMPLICURE AB (publ) (SE) 2025-07-17 US claimed
EP-4565202-A1 ALKALINE INTRAORAL PRODUCTS EMPLICURE AB (publ) (SE) 2025-06-11 EP claimed
WO-2024254056-A1 MODIFIED RELEASE FILL COMPOSITIONS FOR DOSAGE FORMS AND METHODS OF PREPARATION AND USE THEREOF CATALENT ONTARIO LIMITED (CA) 2024-12-12 WO claimed
US-12133922-B2 Abuse resistant capsule R.P. SCHERER TECHNOLOGIES, LLC (US) 2024-11-05 US claimed
US-20240288374-A1 PLASMONIC NANOPARTICLE PLATFORM FOR ANALYTE DETECTION Zymeron Corporation 2024-08-29 US claimed
WO-2024172892-A1 PLASMONIC NANOPARTICLE PLATFORM FOR ANALYTE DETECTION Zymeron Corporation (US) 2024-08-22 WO claimed
US-12036192-B2 Combination treatments for opioid crisis PRESTI MICHAEL (US) 2024-07-16 US claimed
US-5654281-A Inhibiting the development of tolerance to and/or dependence on an addictive substance VIRGINIA COMMONWEALTH UNIVERSITY (US) 1997-08-05 US claimed
EP-0785775-A1 MELT-EXTRUDED ORALLY ADMINISTRABLE OPIOID FORMULATIONS Euroceltique S.A. (LU) 1997-07-30 EP claimed
EP-0731694-A4 1996-10-02 EP claimed
EP-0731694-A1 OPIOID FORMULATIONS FOR TREATING PAIN Euroceltique S.A. (LU) 1996-09-18 EP claimed
CN-1130352-A Method for relieving pain by orally administering 24-hour sustained-release opioid dosage form capable of rapidly increasing initial blood concentration of patient EURO CELTIQUE SA (LU) 1996-09-04 CN claimed
WO-1996014058-A1 MELT-EXTRUDED ORALLY ADMINISTRABLE OPIOID FORMULATIONS EURO-CELTIQUE, S.A. (LU) 1996-05-17 WO claimed
WO-1995014460-A1 OPIOID FORMULATIONS FOR TREATING PAIN EURO-CELTIQUE S.A. (LU) 1995-06-01 WO claimed
EP-0647448-A1 Orally administrable opioid formulations having extended duration of effect Euroceltique S.A. (LU) 1995-04-12 EP claimed
EP-0608893-A1 Inhibiting the development of tolerance to and/or dependence on an additive substance VIRGINIA COMMONWEALTH UNIVERSITY (US) 1994-08-03 EP claimed
US-4126684-A 4-AMINO-3-P-HALOPHENYLBUTYRIC ACIDS AND THEIR DERIVATIVES USED IN THE CONTROL OF NARCOTIC ABUSE CIBA-GEIGY CORPORATION (US) 1978-11-21 US claimed