⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27293304 | 0.85 | GPR84 (0.49) | — | |
| SCHEMBL29474236 | 0.81 | — | — | |
| SCHEMBL10538542 | 0.76 | GPR84 (0.34) | — | |
| SCHEMBL27763230 | 0.74 | GPR84 (0.33) | — | |
| SCHEMBL2958684 | 0.73 | — | — | |
| SCHEMBL28328533 | 0.73 | — | — | |
| SCHEMBL2956839 | 0.73 | — | — | |
| SCHEMBL4688291 | 0.73 | PRKCI (0.32) | — | |
| SCHEMBL3344256 | 0.73 | — | — | |
| SCHEMBL31369337 | 0.71 | GABRA1 (0.39) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3950685-A1 | PYRAZOLOPYRIDINE COMPOUND AS RET INHIBITOR AND APPLICATION THEREOF | Guangzhou Baiyunshan Pharmaceutical Holdings Co., Ltd. Baiyunshan Pharmaceutical General Factory (CN) | 2022-02-09 | — | — | EP | disclosed |