Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IAPP | P10997 | 3/20 | 0.57 |
| ▸ | TAAR1 | Q96RJ0 | 3/20 | 0.49 |
| ▸ | FFAR1 | O14842 | 2/20 | 0.47 |
| ▸ | FFAR4 | Q5NUL3 | 2/20 | 0.47 |
| ▸ | ESR1 | P03372 | 1/20 | 0.46 |
| ▸ | NR3C1 | P04150 | 1/20 | 0.46 |
| ▸ | PGR | P06401 | 1/20 | 0.46 |
| ▸ | NR3C2 | P08235 | 1/20 | 0.46 |
| ▸ | AR | P10275 | 1/20 | 0.46 |
| ▸ | THRA | P10827 | 1/20 | 0.46 |
| ▸ | THRB | P10828 | 1/20 | 0.46 |
| ▸ | RIPK1 | Q13546 | 1/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.44 |
| ▸ | NPC1 | O15118 | 1/20 | 0.43 |
| ▸ | RAB9A | P51151 | 1/20 | 0.43 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7332798 | 0.91 | TAAR1 (0.57) | TAAR1FFAR1FFAR4ESR1NR3C1 | |
| SCHEMBL27670498 | 0.81 | TAAR1 (0.50) | TAAR1RIPK1L3MBTL1NPC1RAB9A | |
| SCHEMBL110045 | 0.81 | IAPP (0.58) | IAPPTAAR1FFAR4NR3C2THRA | |
| SCHEMBL4234560 | 0.81 | ALDH1A1 (0.60) | TAAR1FFAR1FFAR4ESR1NR3C1 | |
| SCHEMBL24242075 | 0.81 | FFAR1 (0.48) | TAAR1FFAR1FFAR4ESR1NR3C1 | |
| SCHEMBL22699217 | 0.80 | TAAR1 (0.49) | TAAR1FFAR1FFAR4ESR1NR3C1 | |
| SCHEMBL28210558 | 0.80 | FFAR1 (0.57) | TAAR1FFAR1FFAR4ESR1NR3C1 | |
| SCHEMBL4151444 | 0.79 | TAAR1 (0.45) | TAAR1FFAR1FFAR4ESR1NR3C1 | |
| SCHEMBL9709577 | 0.79 | IAPP (0.59) | IAPPTAAR1FFAR1FFAR4 | |
| SCHEMBL6586 | 0.79 | FFAR1 (0.68) | TAAR1FFAR1FFAR4ESR1NR3C1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3728235-B1 | SUBSTITUTED THIOPHENYLURACILS , THEIR SALTS AND USE OF SAID COMPOUNDS AS HERBICIDAL AGENTS | SYNGENTA CROP PROTECTION AG (CH) | 2022-02-09 | — | — | EP | disclosed |