Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADAMTS4 | O75173 | 11/20 | 0.65 |
| ▸ | MMP13 | P45452 | 6/20 | 0.65 |
| ▸ | AR | P10275 | 5/20 | 0.56 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.56 |
| ▸ | POLB | P06746 | 2/20 | 0.56 |
| ▸ | MMP1 | P03956 | 1/20 | 0.55 |
| ▸ | MMP2 | P08253 | 1/20 | 0.55 |
| ▸ | MMP9 | P14780 | 1/20 | 0.55 |
| ▸ | MMP14 | P50281 | 1/20 | 0.55 |
| ▸ | ADAM17 | P78536 | 1/20 | 0.55 |
| ▸ | ADAMTS5 | Q9UNA0 | 1/20 | 0.55 |
| ▸ | CA12 | O43570 | 1/20 | 0.54 |
| ▸ | CA1 | P00915 | 1/20 | 0.54 |
| ▸ | CA2 | P00918 | 1/20 | 0.54 |
| ▸ | CA4 | P22748 | 1/20 | 0.54 |
| ▸ | CA5A | P35218 | 1/20 | 0.54 |
| ▸ | CA7 | P43166 | 1/20 | 0.54 |
| ▸ | CA9 | Q16790 | 1/20 | 0.54 |
| ▸ | CA5B | Q9Y2D0 | 1/20 | 0.54 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6325732 | 1.00 | ADAMTS4 (0.65) | ADAMTS4MMP13ARALDH1A1POLB | |
| SCHEMBL6325729 | 1.00 | ADAMTS4 (0.65) | ADAMTS4MMP13ARALDH1A1POLB | |
| SCHEMBL31310984 | 0.81 | SMN1; SMN2 (0.67) | ADAMTS4MMP13ALDH1A1POLBMMP1 | |
| SCHEMBL31310982 | 0.81 | SMN1; SMN2 (0.67) | ADAMTS4MMP13ALDH1A1POLBMMP1 | |
| SCHEMBL6240936 | 0.80 | ADAMTS4 (0.70) | ADAMTS4MMP13MMP2MMP14ADAMTS5 | |
| SCHEMBL6323743 | 0.80 | MMP13 (0.54) | ADAMTS4MMP13ALDH1A1POLBMMP1 | |
| SCHEMBL1656170 | 0.79 | ADAMTS4 (1.00) | ADAMTS4MMP13MMP2MMP14ADAMTS5 | |
| SCHEMBL12730470 | 0.79 | ADAMTS4 (1.00) | ADAMTS4MMP13MMP2MMP14ADAMTS5 | |
| SCHEMBL17286587 | 0.79 | ADAMTS4 (0.62) | ADAMTS4MMP13ARALDH1A1POLB | |
| SCHEMBL6325735 | 0.79 | ADAMTS4 (0.62) | ADAMTS4MMP13ARPOLBMMP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-118221656-A | Compounds useful for the treatment of gastrointestinal disorders | 阿德利克斯股份有限公司 | 2024-06-21 | — | — | CN | disclosed |
| CN-110267944-B | Compounds useful for the treatment of gastrointestinal disorders | 阿德利克斯股份有限公司 | 2024-03-08 | — | — | CN | disclosed |
| US-11242337-B2 | Compounds useful for treating gastrointestinal tract disorders | ARDELYX, INC. (US) | 2022-02-08 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11242337-B2 | Compounds useful for treating gastrointestinal tract disorders | SLC10A2, FABP2, SLC10A1 | ADAMTS4 3282/4885MMP13 1803/4885AR 1714/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.