Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | OPRD1 | P41143 | 2/20 | 0.38 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.38 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.35 |
| ▸ | OPRK1 | P41145 | 5/20 | 0.33 |
| ▸ | ADRA2A | P08913 | 2/20 | 0.33 |
| ▸ | ADRA2B | P18089 | 2/20 | 0.33 |
| ▸ | ADRA2C | P18825 | 2/20 | 0.33 |
| ▸ | HRH3 | Q9Y5N1 | 2/20 | 0.33 |
| ▸ | MAPT | P10636 | 2/20 | 0.33 |
| ▸ | ADRA1A | P35348 | 2/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | DRD2 | P14416 | 1/20 | 0.33 |
| ▸ | HTR2A | P28223 | 1/20 | 0.33 |
| ▸ | HRH1 | P35367 | 1/20 | 0.33 |
| ▸ | DRD3 | P35462 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | RAD52 | P43351 | 1/20 | 0.33 |
| ▸ | ADRA1D | P25100 | 1/20 | 0.32 |
| ▸ | ADRA1B | P35368 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8159164 | 0.86 | SIGMAR1 (0.40) | OPRD1OPRM1SIGMAR1OPRK1DRD2 | |
| SCHEMBL2175514 | 0.84 | OPRM1 (0.38) | OPRD1OPRM1SIGMAR1OPRK1ADRA2A | |
| SCHEMBL4959156 | 0.80 | SIGMAR1 (0.35) | OPRD1OPRM1SIGMAR1OPRK1ADRA2A | |
| SCHEMBL4502992 | 0.80 | SIGMAR1 (0.35) | OPRD1OPRM1SIGMAR1OPRK1ADRA2A | |
| SCHEMBL10641032 | 0.78 | ADRA2A (0.40) | OPRD1OPRM1SIGMAR1OPRK1ADRA2A | |
| SCHEMBL82611 | 0.78 | CARM1 (0.48) | OPRD1OPRM1SIGMAR1HRH3KDM4E | |
| SCHEMBL10828056 | 0.78 | SIGMAR1 (0.34) | OPRD1OPRM1SIGMAR1OPRK1ADRA2A | |
| SCHEMBL24491782 | 0.78 | SIGMAR1 (0.34) | OPRD1OPRM1SIGMAR1OPRK1ADRA2A | |
| SCHEMBL3342321 | 0.78 | SIGMAR1 (0.34) | OPRD1OPRM1SIGMAR1OPRK1ADRA2A | |
| SCHEMBL4502994 | 0.78 | KCNA3 (0.35) | OPRD1OPRM1SIGMAR1HRH3KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3950691-A1 | PYRAZOLOPYRIMIDINE DERIVATIVES AS KINASE INHIBITOR | Daewoong Pharmaceutical Co., Ltd. (KR) | 2022-02-09 | — | — | EP | disclosed |