Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR2A | P28223 | 7/20 | 0.71 |
| ▸ | HTR1D | P28221 | 10/20 | 0.55 |
| ▸ | HTR1A | P08908 | 7/20 | 0.55 |
| ▸ | HTR1B | P28222 | 7/20 | 0.55 |
| ▸ | HPGD | P15428 | 1/20 | 0.55 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.55 |
| ▸ | MPO | P05164 | 2/20 | 0.53 |
| ▸ | HTR2C | P28335 | 3/20 | 0.52 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.52 |
| ▸ | HTR2B | P41595 | 3/20 | 0.50 |
| ▸ | HTR3E | A5X5Y0 | 2/20 | 0.50 |
| ▸ | HTR3B | O95264 | 2/20 | 0.50 |
| ▸ | HTR1E | P28566 | 2/20 | 0.50 |
| ▸ | HTR1F | P30939 | 2/20 | 0.50 |
| ▸ | HTR7 | P34969 | 2/20 | 0.50 |
| ▸ | HTR3A | P46098 | 2/20 | 0.50 |
| ▸ | HTR5A | P47898 | 2/20 | 0.50 |
| ▸ | HTR6 | P50406 | 2/20 | 0.50 |
| ▸ | HTR4 | Q13639 | 2/20 | 0.50 |
| ▸ | HTR3D | Q70Z44 | 2/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24243732 | 0.89 | HTR2A (0.59) | HTR2AHTR1DHTR1AHTR1BMPO | |
| SCHEMBL1121997 | 0.87 | HTR1A (0.68) | HTR2AHTR1DHTR1AHTR1BHPGD | |
| Hydrochloric Acid SCHEMBL3869535 | 0.85 | HTR1A (0.67) | HTR2AHTR1DHTR1AHTR1BHPGD | |
| Hydrochloric Acid SCHEMBL7970523 | 0.85 | HTR1A (0.67) | HTR2AHTR1DHTR1AHTR1BHPGD | |
| SCHEMBL24243715 | 0.84 | HTR2A (0.72) | HTR2AHTR1DHTR1AHTR1BMPO | |
| SCHEMBL24243689 | 0.83 | HTR2A (0.72) | HTR2AHTR1DHTR1AHTR1BHPGD | |
| SCHEMBL24243690 | 0.83 | HTR2A (0.71) | HTR2AHTR1DHTR1AHTR1BMPO | |
| SCHEMBL21846788 | 0.83 | HTR1D (0.77) | HTR2AHTR1DHTR1AHTR1BHPGD | |
| SCHEMBL29904441 | 0.83 | HTR2A (1.00) | HTR2AHTR1DHTR1AHTR1BMPO | |
| SCHEMBL24243693 | 0.83 | HTR2A (1.00) | HTR2AHTR1DHTR1AHTR1BMPO |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20220241243-A1 | METHODS OF TREATING MOOD DISORDERS | GILGAMESH PHARMACEUTICALS, INC. | 2022-08-04 | — | — | US | disclosed |
| US-20220041551-A1 | METHODS OF TREATING MOOD DISORDERS | GILGAMESH PHARMACEUTICALS, INC. (US) | 2022-02-10 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20220041551-A1 | METHODS OF TREATING MOOD DISORDERS | GRIN2C, GRIN2A, TPH2 | HTR2A 5/4885HTR1D 53/4885HTR1A 23/4885 |
| US-20220241243-A1 | METHODS OF TREATING MOOD DISORDERS | GRIN2C, GRIN2A, TPH2 | HTR2A 5/4885HTR1D 53/4885HTR1A 23/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.