Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR1A | P08908 | 7/20 | 0.68 |
| ▸ | HTR2C | P28335 | 6/20 | 0.68 |
| ▸ | HTR2A | P28223 | 4/20 | 0.68 |
| ▸ | SLC6A4 | P31645 | 4/20 | 0.68 |
| ▸ | MPO | P05164 | 1/20 | 0.68 |
| ▸ | HTR1D | P28221 | 8/20 | 0.67 |
| ▸ | HTR1B | P28222 | 6/20 | 0.67 |
| ▸ | HTR2B | P41595 | 3/20 | 0.65 |
| ▸ | HTR7 | P34969 | 3/20 | 0.65 |
| ▸ | HTR5A | P47898 | 3/20 | 0.65 |
| ▸ | HTR6 | P50406 | 3/20 | 0.65 |
| ▸ | HTR3E | A5X5Y0 | 2/20 | 0.65 |
| ▸ | HTR3B | O95264 | 2/20 | 0.65 |
| ▸ | HTR1E | P28566 | 2/20 | 0.65 |
| ▸ | HTR1F | P30939 | 2/20 | 0.65 |
| ▸ | HTR3A | P46098 | 2/20 | 0.65 |
| ▸ | HTR4 | Q13639 | 2/20 | 0.65 |
| ▸ | HTR3D | Q70Z44 | 2/20 | 0.65 |
| ▸ | HTR3C | Q8WXA8 | 2/20 | 0.65 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.65 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL3869535 | 0.98 | HTR1A (0.67) | HTR1AHTR2CHTR2ASLC6A4MPO | |
| Hydrochloric Acid SCHEMBL7970523 | 0.98 | HTR1A (0.67) | HTR1AHTR2CHTR2ASLC6A4MPO | |
| SCHEMBL3379714 | 0.91 | SLC6A4 (0.70) | HTR1AHTR2CHTR2ASLC6A4MPO | |
| SCHEMBL1576211 | 0.88 | HTR2A (0.68) | HTR1AHTR2CHTR2ASLC6A4MPO | |
| SCHEMBL24243733 | 0.87 | HTR2A (0.71) | HTR1AHTR2CHTR2ASLC6A4MPO | |
| Dinitrophenylene SCHEMBL27321903 | 0.84 | HTR1A (0.51) | HTR1AHTR2CHTR2ASLC6A4MPO | |
| SCHEMBL29633081 | 0.83 | HTR1A (0.70) | HTR1AHTR2CHTR2ASLC6A4MPO | |
| Hydrochloric Acid SCHEMBL10429786 | 0.83 | CYP2C19 (0.58) | HTR1AHTR2CHTR2ASLC6A4MPO | |
| SCHEMBL4055413 | 0.83 | HTR1A (0.70) | HTR1AHTR2CHTR2ASLC6A4MPO | |
| SCHEMBL8235788 | 0.82 | CYP2C19 (0.63) | HTR1AHTR2CHTR2AMPOHTR1D |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 84 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4590682-A1 | IMPROVED SYNTHESIS OF PSILOCYBIN DERIVATIVES | CARBOGEN AMCIS AG (CH) | 2025-07-30 | — | — | EP | disclosed |
| WO-2024062080-A1 | IMPROVED SYNTHESIS OF PSILOCYBIN DERIVATIVES | CARBOGEN AMCIS AG (CH) | 2024-03-28 | — | — | WO | disclosed |
| US-20140051687-A1 | SUBSTITUTED INDOLE COMPOUNDS HAVING NOS INHIBITORY ACTIVITY | NEURAXON, INC. (CA) | 2014-02-20 | — | — | US | disclosed |
| US-20140051687-A1 | SUBSTITUTED INDOLE COMPOUNDS HAVING NOS INHIBITORY ACTIVITY | NEURAXON, INC. (CA) | 2014-02-20 | — | — | US | disclosed |
| US-20140051687-A1 | SUBSTITUTED INDOLE COMPOUNDS HAVING NOS INHIBITORY ACTIVITY | NEURAXON, INC. (CA) | 2014-02-20 | — | — | US | disclosed |
| US-8586620-B2 | Substituted indole compounds having NOS inhibitory activity | NEURAXON, INC. (CA) | 2013-11-19 | — | — | US | disclosed |
| US-8586620-B2 | Substituted indole compounds having NOS inhibitory activity | NEURAXON, INC. (CA) | 2013-11-19 | — | — | US | disclosed |
| US-20120128768-A1 | ACTIVE SUBSTANCE COMBINATION COMPRISING A COMPOUND WITH NPY RECEPTOR AFFINITY AND A COMPOUND WITH 5-HT6 RECEPTOR AFFINITY | LABORATORIOS DEL DR. ESTEVE S.A (ES) | 2012-05-24 | — | — | US | disclosed |
| US-20110212947-A1 | SUBSTITUTED INDOLE COMPOUNDS HAVING NOS INHIBITORY ACTIVITY | NEURAXON INC. (CA) | 2011-09-01 | — | — | US | disclosed |
| US-20110212947-A1 | SUBSTITUTED INDOLE COMPOUNDS HAVING NOS INHIBITORY ACTIVITY | NEURAXON INC. (CA) | 2011-09-01 | — | — | US | disclosed |
| EP-0768301-A1 | N-(2-substituted-3-(2-aminoethyl)-1H-indol-5-yl)-amides as new 5-HT1F agonists | ELI LILLY AND COMPANY (US) | 1997-04-16 | — | — | EP | disclosed |
| EP-0666858-A1 | 5-ARYLINDOLE DERIVATIVES AND THEIR USE AS SEROTONIN (5-HT 1?) AGONISTS | PFIZER INC. (US) | 1995-08-16 | — | — | EP | disclosed |
| EP-0644187-A1 | Antimigraine cyclobutenedione derivatives of tryptamines | BRISTOL-MYERS SQUIBB COMPANY (US) | 1995-03-22 | — | — | EP | disclosed |
| US-5382592-A | Antimigraine cyclobutenedione derivatives of tryptamines | BRISTOL-MYERS SQUIBB COMPANY (US) | 1995-01-17 | — | — | US | disclosed |
| CN-1094727-A | The 5-(hetero) aryl indole derivatives | PFIZER (US) | 1994-11-09 | — | — | CN | disclosed |
| EP-0619805-A1 | INDOLE DERIVATIVES | PFIZER HOSPITAL PRODUCTS, INC. (US) | 1994-10-19 | — | — | EP | disclosed |
| WO-1994010171-A1 | 5-ARYLINDOLE DERIVATIVES AND THEIR USE AS SEROTONIN (5-HT1) AGONISTS | PFIZER INC. (US) | 1994-05-11 | — | — | WO | disclosed |
| WO-1993011106-A1 | INDOLE DERIVATIVES | PFIZER, INC. (US) | 1993-06-10 | — | — | WO | disclosed |
| CN-1072679-A | INDOLE DERIVATIVES | PFIZER (US) | 1993-06-02 | — | — | CN | disclosed |
| US-4803218-A | HYPOTENSIVE AGENTS | MCNEILAB, INC. (US) | 1989-02-07 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110212947-A1 | SUBSTITUTED INDOLE COMPOUNDS HAVING NOS INHIBITORY ACTIVITY | NOS2, NOS1, NOS3 | HTR1A 91/4885HTR2C 434/4885HTR2A 156/4885 |
| US-20120128768-A1 | ACTIVE SUBSTANCE COMBINATION COMPRISING A COMPOUND WITH NPY RECEPTOR AFFINITY AND A COMPOUND WITH 5-HT6 RECEPTOR AFFINITY | HTR6, NPY5R, NPY2R | HTR1A 12/4885HTR2C 23/4885HTR2A 18/4885 |
| US-20140051687-A1 | SUBSTITUTED INDOLE COMPOUNDS HAVING NOS INHIBITORY ACTIVITY | NOS2, NOS1, NOS3 | HTR1A 91/4885HTR2C 434/4885HTR2A 156/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.