Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR1A | P08908 | 5/20 | 0.58 |
| ▸ | HTR2A | P28223 | 5/20 | 0.58 |
| ▸ | HTR2C | P28335 | 4/20 | 0.58 |
| ▸ | HTR2B | P41595 | 4/20 | 0.58 |
| ▸ | HTR6 | P50406 | 4/20 | 0.56 |
| ▸ | BCHE | P06276 | 5/20 | 0.54 |
| ▸ | SLC6A4 | P31645 | 4/20 | 0.52 |
| ▸ | TRPM8 | Q7Z2W7 | 1/20 | 0.50 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.50 |
| ▸ | LMNA | P02545 | 1/20 | 0.50 |
| ▸ | MAPT | P10636 | 1/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.50 |
| ▸ | ACHE | P22303 | 1/20 | 0.49 |
| ▸ | ADRA2A | P08913 | 3/20 | 0.49 |
| ▸ | ADRA2B | P18089 | 2/20 | 0.49 |
| ▸ | ADRA2C | P18825 | 2/20 | 0.49 |
| ▸ | ADRA1A | P35348 | 2/20 | 0.49 |
| ▸ | HRH1 | P35367 | 2/20 | 0.49 |
| ▸ | ADRA1B | P35368 | 2/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30877886 | 0.82 | MPO (0.62) | HTR1AHTR2AHTR2CHTR2BHTR6 | |
| SCHEMBL24693264 | 0.82 | MPO (0.62) | HTR1AHTR2AHTR2CHTR2BHTR6 | |
| SCHEMBL1969237 | 0.82 | HTR2A (0.68) | HTR1AHTR2AHTR2CHTR2BHTR6 | |
| SCHEMBL24243697 | 0.81 | HTR2A (0.62) | HTR1AHTR2AHTR2CHTR2BHTR6 | |
| SCHEMBL31745763 | 0.80 | HTR2A (0.69) | HTR1AHTR2AHTR2CHTR2BHTR6 | |
| SCHEMBL2761730 | 0.80 | HTR2A (0.69) | HTR1AHTR2AHTR2CHTR2BHTR6 | |
| SCHEMBL24243744 | 0.80 | HTR1A (0.65) | HTR1AHTR2AHTR2CHTR2BHTR6 | |
| SCHEMBL24243762 | 0.79 | HTR1A (0.56) | HTR1AHTR2AHTR2CHTR2BHTR6 | |
| SCHEMBL29206381 | 0.79 | MPO (0.61) | HTR1AHTR2AHTR2CHTR2BHTR6 | |
| SCHEMBL30877823 | 0.79 | MPO (0.61) | HTR1AHTR2AHTR2CHTR2BHTR6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20220041551-A1 | METHODS OF TREATING MOOD DISORDERS | GILGAMESH PHARMACEUTICALS, INC. (US) | 2022-02-10 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20220041551-A1 | METHODS OF TREATING MOOD DISORDERS | GRIN2C, GRIN2A, TPH2 | HTR1A 23/4885HTR2A 5/4885HTR2C 4/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.