Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.50 |
| ▸ | LMNA | P02545 | 1/20 | 0.48 |
| ▸ | USP30 | Q70CQ3 | 2/20 | 0.46 |
| ▸ | SIGMAR1 | Q99720 | 5/20 | 0.46 |
| ▸ | SSTR1 | P30872 | 1/20 | 0.46 |
| ▸ | SSTR4 | P31391 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.45 |
| ▸ | POLB | P06746 | 1/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.44 |
| ▸ | CNR2 | P34972 | 1/20 | 0.44 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23750364 | 1.00 | L3MBTL1 (0.50) | L3MBTL1LMNAUSP30SIGMAR1SSTR1 | |
| SCHEMBL14924027 | 0.92 | L3MBTL1 (0.55) | L3MBTL1LMNASIGMAR1KMT2APOLB | |
| SCHEMBL21624752 | 0.85 | MEN1 (0.50) | L3MBTL1LMNAUSP30SIGMAR1KMT2A | |
| SCHEMBL21624753 | 0.85 | MEN1 (0.50) | L3MBTL1LMNAUSP30SIGMAR1KMT2A | |
| SCHEMBL19226535 | 0.81 | HDAC4 (0.53) | LMNAKMT2A | |
| SCHEMBL27396501 | 0.79 | POLB (0.70) | L3MBTL1LMNAKMT2APOLBALDH1A1 | |
| SCHEMBL29689880 | 0.79 | NPC1 (0.62) | L3MBTL1USP30KMT2AALDH1A1EPHX2 | |
| SCHEMBL26501529 | 0.78 | PANK3 (0.48) | L3MBTL1ALDH1A1 | |
| SCHEMBL26501525 | 0.78 | PANK3 (0.48) | L3MBTL1ALDH1A1 | |
| SCHEMBL21624779 | 0.77 | LMNA (0.55) | L3MBTL1LMNAKMT2APOLBALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3950059-A1 | USE OF T-TYPE CALCIUM CHANNEL BLOCKER FOR TREATING PRURITUS | Nippon Chemiphar Co., Ltd. (JP) | 2022-02-09 | — | — | EP | disclosed |