Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 2/20 | 0.70 |
| ▸ | NPC1 | O15118 | 1/20 | 0.68 |
| ▸ | RAB9A | P51151 | 1/20 | 0.68 |
| ▸ | EPHX2 | P34913 | 4/20 | 0.65 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.64 |
| ▸ | MEN1 | O00255 | 3/20 | 0.61 |
| ▸ | TP53 | P04637 | 1/20 | 0.61 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.61 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.61 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.61 |
| ▸ | RELA | Q04206 | 1/20 | 0.61 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.61 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.60 |
| ▸ | LMNA | P02545 | 3/20 | 0.60 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.58 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.58 |
| ▸ | BCHE | P06276 | 1/20 | 0.56 |
| ▸ | ACHE | P22303 | 1/20 | 0.56 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.56 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25649879 | 0.90 | RAB9A (0.66) | POLBNPC1RAB9AEPHX2KMT2A | |
| SCHEMBL21624779 | 0.85 | LMNA (0.55) | POLBNPC1RAB9AEPHX2KMT2A | |
| SCHEMBL14924027 | 0.84 | L3MBTL1 (0.55) | POLBNPC1RAB9AEPHX2KMT2A | |
| SCHEMBL23130338 | 0.83 | POLB (1.00) | POLBNPC1RAB9AEPHX2KMT2A | |
| SCHEMBL15652941 | 0.83 | RAB9A (0.73) | POLBNPC1RAB9AEPHX2KMT2A | |
| SCHEMBL25893862 | 0.83 | RAB9A (0.73) | POLBNPC1RAB9AEPHX2KMT2A | |
| SCHEMBL23387364 | 0.82 | LMNA (0.50) | POLBNPC1RAB9AEPHX2KMT2A | |
| SCHEMBL5053663 | 0.81 | RAB9A (0.71) | POLBNPC1RAB9AEPHX2KMT2A | |
| SCHEMBL9325905 | 0.81 | NPC1 (1.00) | POLBNPC1RAB9AEPHX2KMT2A | |
| SCHEMBL21424360 | 0.80 | LMNA (0.49) | POLBNPC1RAB9AEPHX2KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024126617-A1 | BIFUNCTIONAL COMPOUNDS FOR DEGRADING KINASES VIA UBIQUITIN PROTEOSOME PATHWAY | CROSSFIRE ONCOLOGY HOLDING B.V. (NL) | 2024-06-20 | — | — | WO | disclosed |