Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A1 | P30531 | 2/20 | 0.41 |
| ▸ | SLC6A11 | P48066 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | SLC6A13 | Q9NSD5 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | ATM | Q13315 | 1/20 | 0.41 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.41 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.39 |
| ▸ | CTSK | P43235 | 1/20 | 0.38 |
| ▸ | CNR1 | P21554 | 2/20 | 0.38 |
| ▸ | DAGLA | Q9Y4D2 | 2/20 | 0.38 |
| ▸ | CCR2 | P41597 | 1/20 | 0.37 |
| ▸ | GNAI3 | P08754 | 1/20 | 0.36 |
| ▸ | GNAO1 | P09471 | 1/20 | 0.36 |
| ▸ | GNAI1 | P63096 | 1/20 | 0.36 |
| ▸ | TLR2 | O60603 | 2/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19034642 | 1.00 | SLC6A1 (0.41) | SLC6A1SLC6A11TSHRLMNASMN1; SMN2 | |
| SCHEMBL24654945 | 0.79 | SLC6A1 (0.45) | SLC6A1SLC6A11TSHRLMNASMN1; SMN2 | |
| SCHEMBL24489216 | 0.79 | TSHR (0.45) | SLC6A1SLC6A11TSHRLMNASMN1; SMN2 | |
| SCHEMBL13610195 | 0.79 | TSHR (0.45) | SLC6A1SLC6A11TSHRLMNASMN1; SMN2 | |
| SCHEMBL31221629 | 0.79 | TSHR (0.45) | SLC6A1SLC6A11TSHRLMNASMN1; SMN2 | |
| SCHEMBL21105823 | 0.78 | PRCP (0.56) | EPHX2CNR1DAGLACCR2GNAI3 | |
| SCHEMBL9763166 | 0.77 | KDM4E (0.45) | SLC6A1SLC6A11TSHRLMNASMN1; SMN2 | |
| SCHEMBL5371363 | 0.77 | EPHX2 (0.47) | MAPTEPHX2CTSKCNR1DAGLA | |
| SCHEMBL25132726 | 0.76 | FFAR4 (0.47) | TSHRMAPTKMT2AGNAI3GNAO1 | |
| SCHEMBL6050362 | 0.76 | SLC6A1 (0.47) | SLC6A1SLC6A11TSHRLMNASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11679158-B2 | Biodegradable lipids for the delivery of active agents | ALNYLAM PHARMACEUTICALS, INC. (US) | 2023-06-20 | — | — | US | disclosed |
| US-11246933-B1 | Biodegradable lipids for the delivery of active agents | ALNYLAM PHARMACEUTICALS, INC. (US) | 2022-02-15 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11246933-B1 | Biodegradable lipids for the delivery of active agents | LIPA, APOB, CETP | SLC6A1 3872/4885SLC6A11 3788/4885TSHR 2733/4885 |
| US-11679158-B2 | Biodegradable lipids for the delivery of active agents | LIPA, APOB, CETP | SLC6A1 3872/4885SLC6A11 3788/4885TSHR 2733/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.