Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.45 |
| ▸ | MAPT | P10636 | 1/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.45 |
| ▸ | ATM | Q13315 | 1/20 | 0.45 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.45 |
| ▸ | SLC6A1 | P30531 | 2/20 | 0.42 |
| ▸ | SLC6A11 | P48066 | 1/20 | 0.42 |
| ▸ | TSHR | P16473 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.42 |
| ▸ | SLC6A13 | Q9NSD5 | 1/20 | 0.42 |
| ▸ | NOS2 | P35228 | 1/20 | 0.38 |
| ▸ | BCHE | P06276 | 2/20 | 0.38 |
| ▸ | METAP1 | P53582 | 1/20 | 0.38 |
| ▸ | GRIK1 | P39086 | 1/20 | 0.37 |
| ▸ | GRIK2 | Q13002 | 1/20 | 0.37 |
| ▸ | GNAI3 | P08754 | 2/20 | 0.37 |
| ▸ | GNAO1 | P09471 | 2/20 | 0.37 |
| ▸ | GNAI1 | P63096 | 2/20 | 0.37 |
| ▸ | NAAA | Q02083 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17688564 | 0.82 | NAAA (0.49) | MAPTKMT2ACYP2D6BCHEMETAP1 | |
| SCHEMBL28843002 | 0.82 | NAAA (0.49) | MAPTKMT2ACYP2D6BCHEMETAP1 | |
| SCHEMBL24246397 | 0.77 | SLC6A1 (0.41) | KDM4EMAPTKMT2AATMCYP2D6 | |
| SCHEMBL19034642 | 0.77 | SLC6A1 (0.41) | KDM4EMAPTKMT2AATMCYP2D6 | |
| SCHEMBL13259749 | 0.74 | TSHR (0.47) | KDM4EMAPTKMT2AATMCYP2D6 | |
| SCHEMBL2880053 | 0.73 | SLC6A1 (0.50) | KDM4EMAPTKMT2AATMCYP2D6 | |
| SCHEMBL25022204 | 0.71 | NAAA (0.68) | BCHEGNAI3GNAO1GNAI1NAAA | |
| SCHEMBL24489216 | 0.71 | TSHR (0.45) | KDM4EMAPTKMT2AATMCYP2D6 | |
| SCHEMBL25022735 | 0.71 | NAAA (0.68) | BCHEGNAI3GNAO1GNAI1NAAA | |
| SCHEMBL13610195 | 0.71 | TSHR (0.45) | KDM4EMAPTKMT2AATMCYP2D6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4994462-A | N,N-Bis(nipecotyl)piperazines | RESEARCH CORPORATION (US) | 1991-02-19 | — | — | US | disclosed |
| US-4798830-A | TETRAHYDROQUINOLINE DERIVATIVES | RESEARCH CORPORATION (US) | 1989-01-17 | — | — | US | disclosed |
| US-4634709-A | PIPERIDINE DERIVATIVES | RESEARCH CORPORATION (US) | 1987-01-06 | — | — | US | disclosed |
| US-4443450-A | N,N*-BIS(NIPECOTYL) PIPERAZINE | RESEARCH CORPORATION (US) | 1984-04-17 | — | — | US | disclosed |