Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 2/20 | 0.59 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.55 |
| ▸ | P2RX4 | Q99571 | 1/20 | 0.52 |
| ▸ | RXFP1 | Q9HBX9 | 2/20 | 0.52 |
| ▸ | MAPT | P10636 | 2/20 | 0.52 |
| ▸ | THRB | P10828 | 1/20 | 0.51 |
| ▸ | TP53 | P04637 | 3/20 | 0.51 |
| ▸ | POLB | P06746 | 2/20 | 0.51 |
| ▸ | MEN1 | O00255 | 2/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.50 |
| ▸ | ATM | Q13315 | 1/20 | 0.50 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.50 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.50 |
| ▸ | GAA | P10253 | 1/20 | 0.49 |
| ▸ | HTT | P42858 | 2/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24030794 | 0.83 | HDAC1 (0.73) | HTT | |
| SCHEMBL29381775 | 0.83 | HDAC1 (0.73) | HTT | |
| SCHEMBL16674525 | 0.83 | TSHR (0.73) | TSHRALDH1A1P2RX4MAPTTHRB | |
| SCHEMBL30482352 | 0.81 | TSHR (0.55) | TSHRALDH1A1THRBMEN1KMT2A | |
| SCHEMBL16668021 | 0.76 | HDAC1 (0.67) | TSHRALDH1A1P2RX4MAPTTHRB | |
| SCHEMBL24247607 | 0.76 | HDAC1 (0.73) | TSHRMAPTTHRBTP53MEN1 | |
| SCHEMBL24031181 | 0.76 | THRB (0.71) | TSHRP2RX4MAPTTHRBTP53 | |
| SCHEMBL24247586 | 0.75 | HDAC1 (0.69) | TSHRALDH1A1P2RX4MAPTTHRB | |
| SCHEMBL24030776 | 0.75 | HDAC1 (0.75) | — | |
| SCHEMBL17241596 | 0.75 | TSHR (0.62) | TSHRALDH1A1P2RX4MAPTTP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3624804-B1 | HISTONE DEACETYLASES (HDACS) INHIBITORS | ANNJI PHARM CO LTD (TW) | 2022-02-16 | — | — | EP | disclosed |