Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD17B2 | P37059 | 1/20 | 0.40 |
| ▸ | BRD4 | O60885 | 2/20 | 0.38 |
| ▸ | CREBBP | Q92793 | 2/20 | 0.38 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.38 |
| ▸ | TRPV1 | Q8NER1 | 9/20 | 0.36 |
| ▸ | NTRK1 | P04629 | 1/20 | 0.35 |
| ▸ | DRD2 | P14416 | 1/20 | 0.34 |
| ▸ | HTR2A | P28223 | 1/20 | 0.34 |
| ▸ | DRD3 | P35462 | 1/20 | 0.34 |
| ▸ | SMPD3 | Q9NY59 | 1/20 | 0.33 |
| ▸ | CCR2 | P41597 | 1/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24251594 | 0.88 | HSD17B2 (0.40) | HSD17B2BRD4CREBBPP2RX7TRPV1 | |
| SCHEMBL24251441 | 0.87 | PDE2A (0.42) | — | |
| SCHEMBL24251432 | 0.86 | BRD4 (0.40) | HSD17B2BRD4CREBBPP2RX7TRPV1 | |
| SCHEMBL24251450 | 0.85 | HSD17B2 (0.39) | HSD17B2BRD4CREBBPP2RX7TRPV1 | |
| SCHEMBL24251365 | 0.82 | P2RX7 (0.40) | HSD17B2BRD4CREBBPP2RX7TRPV1 | |
| SCHEMBL24251414 | 0.79 | HSD17B2 (0.38) | HSD17B2P2RX7TRPV1NTRK1 | |
| SCHEMBL24251434 | 0.78 | HSD17B2 (0.44) | HSD17B2BRD4CREBBPP2RX7TRPV1 | |
| SCHEMBL24251462 | 0.77 | HSD17B2 (0.42) | HSD17B2BRD4CREBBPP2RX7TRPV1 | |
| SCHEMBL24251558 | 0.77 | HPGD (0.40) | HSD17B2TRPV1 | |
| SCHEMBL24251353 | 0.76 | BRD4 (0.42) | HSD17B2BRD4CREBBPP2RX7TRPV1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20220048903-A1 | Anthelminthic Heterocyclic Compounds | BOEHRINGER INGELHEIM VETMEDICA GMBH (DE) | 2022-02-17 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20220048903-A1 | Anthelminthic Heterocyclic Compounds | SDHA, PAH, PIGS | HSD17B2 909/4885BRD4 2177/4885CREBBP 4217/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.