Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NTRK1 | P04629 | 1/20 | 0.38 |
| ▸ | XIAP | P98170 | 1/20 | 0.38 |
| ▸ | P2RX7 | Q99572 | 2/20 | 0.37 |
| ▸ | BDKRB1 | P46663 | 2/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.36 |
| ▸ | ADA | P00813 | 2/20 | 0.35 |
| ▸ | CRHBP | P24387 | 1/20 | 0.35 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | TAS1R3 | Q7RTX0 | 1/20 | 0.35 |
| ▸ | TAS1R1 | Q7RTX1 | 1/20 | 0.35 |
| ▸ | TAS1R2 | Q8TE23 | 1/20 | 0.35 |
| ▸ | BRD4 | O60885 | 2/20 | 0.34 |
| ▸ | CREBBP | Q92793 | 2/20 | 0.34 |
| ▸ | TRPV1 | Q8NER1 | 2/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24251415 | 0.87 | TAS1R3 (0.46) | CRHBPCRHR2SMN1; SMN2TAS1R3TAS1R1 | |
| SCHEMBL24251449 | 0.84 | BRD4 (0.38) | NTRK1XIAPP2RX7BDKRB1MAPK1 | |
| SCHEMBL24251353 | 0.81 | BRD4 (0.42) | NTRK1P2RX7BDKRB1MAPK1TAS1R3 | |
| SCHEMBL20547236 | 0.80 | NTRK1 (0.38) | NTRK1XIAPP2RX7MAPK1BRD4 | |
| SCHEMBL24251426 | 0.79 | BRD4 (0.36) | NTRK1XIAPP2RX7BDKRB1MAPK1 | |
| SCHEMBL24251432 | 0.79 | BRD4 (0.40) | NTRK1P2RX7BDKRB1MAPK1TAS1R3 | |
| SCHEMBL24251375 | 0.79 | BRD4 (0.38) | NTRK1P2RX7BDKRB1MAPK1TAS1R3 | |
| SCHEMBL24251352 | 0.79 | BRD4 (0.38) | NTRK1P2RX7BDKRB1MAPK1TAS1R3 | |
| SCHEMBL24251366 | 0.78 | NTRK1 (0.38) | NTRK1P2RX7BDKRB1MAPK1TAS1R3 | |
| SCHEMBL24251595 | 0.77 | CNR1 (0.39) | NTRK1P2RX7MAPK1BRD4CREBBP |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20220048903-A1 | Anthelminthic Heterocyclic Compounds | BOEHRINGER INGELHEIM VETMEDICA GMBH (DE) | 2022-02-17 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20220048903-A1 | Anthelminthic Heterocyclic Compounds | SDHA, PAH, PIGS | NTRK1 4846/4885XIAP 2877/4885P2RX7 781/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.