Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD17B2 | P37059 | 1/20 | 0.38 |
| ▸ | P2RX7 | Q99572 | 2/20 | 0.38 |
| ▸ | BRD4 | O60885 | 2/20 | 0.38 |
| ▸ | CREBBP | Q92793 | 2/20 | 0.38 |
| ▸ | TAS1R3 | Q7RTX0 | 4/20 | 0.35 |
| ▸ | TAS1R1 | Q7RTX1 | 4/20 | 0.35 |
| ▸ | TAS1R2 | Q8TE23 | 4/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | NTRK1 | P04629 | 1/20 | 0.35 |
| ▸ | BDKRB1 | P46663 | 4/20 | 0.35 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | HPGD | P15428 | 1/20 | 0.34 |
| ▸ | CNR1 | P21554 | 1/20 | 0.33 |
| ▸ | CNR2 | P34972 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24251517 | 0.94 | HSD17B2 (0.41) | HSD17B2BRD4CREBBPTAS1R3TAS1R1 | |
| SCHEMBL24251515 | 0.89 | HSD17B2 (0.40) | HSD17B2BRD4CREBBPTAS1R3TAS1R1 | |
| SCHEMBL24251434 | 0.88 | HSD17B2 (0.44) | HSD17B2P2RX7BRD4CREBBPTAS1R3 | |
| SCHEMBL24251567 | 0.88 | P2RX7 (0.38) | HSD17B2P2RX7BRD4CREBBPTAS1R3 | |
| SCHEMBL24251365 | 0.88 | P2RX7 (0.40) | HSD17B2P2RX7BRD4CREBBPTAS1R3 | |
| SCHEMBL23355445 | 0.86 | P2RX7 (0.40) | HSD17B2P2RX7BRD4CREBBPTAS1R3 | |
| SCHEMBL30933444 | 0.86 | P2RX7 (0.40) | HSD17B2P2RX7BRD4CREBBPTAS1R3 | |
| SCHEMBL24251354 | 0.82 | BRD4 (0.40) | HSD17B2BRD4CREBBPTAS1R3TAS1R1 | |
| SCHEMBL23355416 | 0.82 | BRD4 (0.40) | HSD17B2BRD4CREBBPTAS1R3TAS1R1 | |
| SCHEMBL24251356 | 0.81 | BRD4 (0.41) | HSD17B2BRD4CREBBPTAS1R3TAS1R1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20220048903-A1 | Anthelminthic Heterocyclic Compounds | BOEHRINGER INGELHEIM VETMEDICA GMBH (DE) | 2022-02-17 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20220048903-A1 | Anthelminthic Heterocyclic Compounds | SDHA, PAH, PIGS | HSD17B2 909/4885P2RX7 781/4885BRD4 2177/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.