Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TAS1R3 | Q7RTX0 | 6/20 | 0.44 |
| ▸ | TAS1R1 | Q7RTX1 | 6/20 | 0.44 |
| ▸ | TAS1R2 | Q8TE23 | 5/20 | 0.44 |
| ▸ | PDE2A | O00408 | 1/20 | 0.43 |
| ▸ | KCNA5 | P22460 | 1/20 | 0.43 |
| ▸ | CNR1 | P21554 | 1/20 | 0.42 |
| ▸ | PDE10A | Q9Y233 | 2/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.41 |
| ▸ | CNR2 | P34972 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.41 |
| ▸ | LMNA | P02545 | 2/20 | 0.41 |
| ▸ | CRHBP | P24387 | 1/20 | 0.41 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.41 |
| ▸ | SPR | P35270 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24251449 | 0.87 | BRD4 (0.38) | TAS1R3TAS1R1TAS1R2 | |
| SCHEMBL24251550 | 0.86 | PDE2A (0.42) | TAS1R3TAS1R1TAS1R2PDE2APDE10A | |
| SCHEMBL24251374 | 0.85 | TAS1R3 (0.49) | TAS1R3TAS1R1TAS1R2PDE2AKCNA5 | |
| SCHEMBL24251396 | 0.85 | TAS1R3 (0.48) | TAS1R3TAS1R1TAS1R2PDE2AKCNA5 | |
| SCHEMBL24251415 | 0.84 | TAS1R3 (0.46) | TAS1R3TAS1R1TAS1R2PDE2AKCNA5 | |
| SCHEMBL24251368 | 0.82 | TAS1R3 (0.45) | TAS1R3TAS1R1TAS1R2PDE2ACNR1 | |
| SCHEMBL24251369 | 0.82 | TAS1R3 (0.45) | TAS1R3TAS1R1TAS1R2PDE2AKCNA5 | |
| SCHEMBL31171097 | 0.80 | PDE2A (0.48) | TAS1R3TAS1R1TAS1R2PDE2AKCNA5 | |
| SCHEMBL24251426 | 0.79 | BRD4 (0.36) | — | |
| SCHEMBL24251512 | 0.77 | TAS1R3 (0.43) | TAS1R3TAS1R1TAS1R2PDE2ACNR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20220048903-A1 | Anthelminthic Heterocyclic Compounds | BOEHRINGER INGELHEIM VETMEDICA GMBH (DE) | 2022-02-17 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20220048903-A1 | Anthelminthic Heterocyclic Compounds | SDHA, PAH, PIGS | TAS1R3 4103/4885TAS1R1 3604/4885TAS1R2 3646/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.