Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 2/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.35 |
| ▸ | USP2 | O75604 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | HPGD | P15428 | 1/20 | 0.35 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.35 |
| ▸ | RECQL | P46063 | 1/20 | 0.35 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | PTK2B | Q14289 | 1/20 | 0.30 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22661221 | 0.92 | KDM4E (0.38) | KMT2AKDM4EMEN1 | |
| SCHEMBL24251777 | 0.90 | POLB (0.34) | KMT2AKDM4EPOLBALDH1A1USP2 | |
| SCHEMBL22661223 | 0.83 | KDM4E (0.36) | KMT2AKDM4EMEN1 | |
| Methyl Alcohol SCHEMBL20552308 | 0.82 | LMNA (0.33) | KMT2AKDM4EPOLB | |
| SCHEMBL3664084 | 0.81 | LMNA (0.32) | POLB | |
| SCHEMBL27558458 | 0.79 | LMNA (0.31) | — | |
| SCHEMBL13091422 | 0.79 | KDM4E (0.36) | KMT2AKDM4EMEN1 | |
| SCHEMBL9141567 | 0.79 | KDM4E (0.36) | KMT2AKDM4EMEN1 | |
| SCHEMBL9479622 | 0.75 | NOTUM (0.34) | POLBALDH1A1MAPTRECQL | |
| SCHEMBL9563941 | 0.75 | POLB (0.35) | KDM4EPOLBALDH1A1USP2HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20220048852-A1 | PROCESS OF PREPARING IOSIMENOL | OTSUKA PHARMA CO LTD (JP) | 2022-02-17 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20220048852-A1 | PROCESS OF PREPARING IOSIMENOL | AOC2, SSTR2, NISCH | KMT2A 2291/4885KDM4E 2154/4885POLB 1889/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.