Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.50 |
| ▸ | MAPT | P10636 | 3/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.45 |
| ▸ | NPC1 | O15118 | 1/20 | 0.45 |
| ▸ | RAB9A | P51151 | 1/20 | 0.45 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.45 |
| ▸ | ALDH1A3 | P47895 | 1/20 | 0.45 |
| ▸ | GAA | P10253 | 4/20 | 0.44 |
| ▸ | HTT | P42858 | 3/20 | 0.44 |
| ▸ | S100B | P04271 | 3/20 | 0.44 |
| ▸ | MEN1 | O00255 | 3/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.44 |
| ▸ | LMNA | P02545 | 2/20 | 0.44 |
| ▸ | PKM | P14618 | 1/20 | 0.44 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.44 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.44 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.44 |
| ▸ | POLB | P06746 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20764155 | 0.89 | MAPT (0.58) | ALDH1A1MAPTKDM4ESMN1; SMN2NPC1 | |
| SCHEMBL10810169 | 0.87 | ALDH1A1 (0.57) | ALDH1A1MAPTKDM4ESMN1; SMN2NPC1 | |
| SCHEMBL17059208 | 0.86 | DRD2 (0.53) | ALDH1A1MAPTKDM4EGAAHTT | |
| SCHEMBL29930028 | 0.86 | DRD2 (0.53) | ALDH1A1MAPTKDM4EGAAHTT | |
| SCHEMBL6819654 | 0.84 | GAA (0.55) | ALDH1A1MAPTKDM4ESMN1; SMN2NPC1 | |
| SCHEMBL22003311 | 0.84 | LGMN (0.50) | ALDH1A1MAPTKDM4ESMN1; SMN2NPC1 | |
| SCHEMBL6819147 | 0.83 | GAA (0.53) | ALDH1A1MAPTKDM4ESMN1; SMN2NPC1 | |
| SCHEMBL30505441 | 0.83 | LGMN (0.49) | ALDH1A1MAPTKDM4ESMN1; SMN2NPC1 | |
| SCHEMBL30108190 | 0.83 | ALDH1A1 (0.51) | ALDH1A1MAPTKDM4ENPC1RAB9A | |
| SCHEMBL28087914 | 0.79 | CCR4 (0.40) | ALDH1A1MAPTKDM4ENPC1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022033455-A1 | TRIAZINE DERIVATIVE HAVING EGFR INHIBITORY ACTIVITY, PREPARATION METHOD THEREFOR AND USE THEREOF | 上海和誉生物医药科技有限公司 | 2022-02-17 | — | — | WO | disclosed |