Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NR1H4 | Q96RI1 | 1/20 | 0.59 |
| ▸ | CTSS | P25774 | 1/20 | 0.46 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.46 |
| ▸ | PLK1 | P53350 | 2/20 | 0.44 |
| ▸ | GAA | P10253 | 2/20 | 0.42 |
| ▸ | NPC1 | O15118 | 3/20 | 0.40 |
| ▸ | RAB9A | P51151 | 3/20 | 0.40 |
| ▸ | JAK1 | P23458 | 2/20 | 0.40 |
| ▸ | TYK2 | P29597 | 2/20 | 0.40 |
| ▸ | TP53 | P04637 | 2/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
| ▸ | APEX1 | P27695 | 3/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6024762 | 0.86 | CTSS (0.61) | NR1H4CTSSMTNR1APLK1GAA | |
| SCHEMBL24252034 | 0.83 | NR1H4 (0.58) | NR1H4CTSSNPC1RAB9AJAK1 | |
| SCHEMBL7796386 | 0.81 | NR1H4 (0.56) | NR1H4CTSSHPGDAPEX1ALDH1A1 | |
| SCHEMBL1601264 | 0.81 | NR1H4 (0.53) | NR1H4NPC1RAB9A | |
| SCHEMBL20288226 | 0.80 | NR1H4 (0.51) | NR1H4CTSSALDH1A1MAPT | |
| SCHEMBL8609341 | 0.80 | NR1H4 (0.55) | NR1H4CTSSNPC1RAB9ASMN1; SMN2 | |
| SCHEMBL2652368 | 0.80 | NPC1 (0.50) | MTNR1APLK1GAANPC1RAB9A | |
| SCHEMBL8104116 | 0.79 | GAA (0.55) | NR1H4PLK1GAAHPGDALDH1A1 | |
| SCHEMBL1534502 | 0.78 | RAB9A (0.61) | PLK1GAANPC1RAB9ATP53 | |
| SCHEMBL16952702 | 0.78 | NR1H4 (0.48) | NR1H4CTSSTP53SMN1; SMN2HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20220048915-A1 | Nitrogen-containing Heterocyclic Compound and Composition Thereof, Preparation Method Therefor, and Application Thereof | SHANGHAI PHARMACEUTICALS HOLDING CO., LTD. (CN) | 2022-02-17 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20220048915-A1 | Nitrogen-containing Heterocyclic Compound and Composition Thereof, Preparation Method Therefor, and Application Thereof | MAPK11, WEE1, NOS1 | NR1H4 1506/4885CTSS 4371/4885MTNR1A 3350/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.