Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP2D6 | P10635 | 1/20 | 0.46 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.46 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.46 |
| ▸ | NPC1 | O15118 | 2/20 | 0.46 |
| ▸ | RAB9A | P51151 | 2/20 | 0.46 |
| ▸ | METAP2 | P50579 | 3/20 | 0.44 |
| ▸ | METAP1 | P53582 | 3/20 | 0.44 |
| ▸ | TSHR | P16473 | 1/20 | 0.43 |
| ▸ | MMP8 | P22894 | 1/20 | 0.42 |
| ▸ | MMP14 | P50281 | 1/20 | 0.42 |
| ▸ | LAP3 | P28838 | 2/20 | 0.42 |
| ▸ | ANPEP | P15144 | 1/20 | 0.42 |
| ▸ | RNPEP | Q9H4A4 | 1/20 | 0.42 |
| ▸ | DNPEP | Q9ULA0 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | PKM | P14618 | 1/20 | 0.42 |
| ▸ | MMP3 | P08254 | 1/20 | 0.41 |
| ▸ | MMP2 | P08253 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16156196 | 1.00 | CYP2D6 (0.46) | CYP2D6CYP2C9CYP2C19KMT2ANPC1 | |
| SCHEMBL24252140 | 0.85 | NPC1 (0.51) | KMT2ANPC1RAB9ALAP3ANPEP | |
| SCHEMBL6190476 | 0.79 | KMT2A (0.48) | CYP2D6CYP2C9CYP2C19KMT2ATSHR | |
| SCHEMBL16156176 | 0.79 | KMT2A (0.48) | CYP2D6CYP2C9CYP2C19KMT2ATSHR | |
| SCHEMBL16149006 | 0.79 | KMT2A (0.48) | CYP2D6CYP2C9CYP2C19KMT2ATSHR | |
| SCHEMBL16898255 | 0.79 | NPC1 (0.46) | NPC1RAB9AMETAP2METAP1TSHR | |
| SCHEMBL16450802 | 0.79 | NPC1 (0.54) | NPC1RAB9A | |
| SCHEMBL24252168 | 0.78 | GRIK1 (0.50) | CYP2D6CYP2C9CYP2C19KMT2ANPC1 | |
| SCHEMBL17510916 | 0.78 | GRIK1 (0.50) | CYP2D6CYP2C9CYP2C19KMT2ANPC1 | |
| SCHEMBL4290341 | 0.78 | GRIK1 (0.50) | CYP2D6CYP2C9CYP2C19KMT2ANPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230364272-A1 | THERANOSTIC COMPOUNDS | UNIVERSITY OF CAPE TOWN (ZA) | 2023-11-16 | — | — | US | disclosed |
| US-20230364272-A1 | THERANOSTIC COMPOUNDS | UNIVERSITY OF CAPE TOWN (ZA) | 2023-11-16 | — | — | US | disclosed |
| WO-2022034544-A1 | THERANOSTIC COMPOUNDS | NRF ITHEMBA LABS (ZA) | 2022-02-17 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230364272-A1 | THERANOSTIC COMPOUNDS | MMP12, TIMP3, CTSZ | CYP2D6 2731/4885CYP2C9 2341/4885CYP2C19 2006/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.