Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NAAA | Q02083 | 7/20 | 0.47 |
| ▸ | PPARA | Q07869 | 1/20 | 0.45 |
| ▸ | FAAH | O00519 | 4/20 | 0.45 |
| ▸ | IL6ST | P40189 | 1/20 | 0.43 |
| ▸ | ACE | P12821 | 2/20 | 0.38 |
| ▸ | IDH1 | O75874 | 5/20 | 0.38 |
| ▸ | PTGER2 | P43116 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12567858 | 0.90 | PPARA (0.51) | NAAAPPARAFAAHIL6STACE | |
| SCHEMBL28895898 | 0.88 | PPARA (0.51) | NAAAPPARAFAAHIL6STACE | |
| SCHEMBL15587060 | 0.88 | PPARA (0.51) | NAAAPPARAFAAHIL6STACE | |
| SCHEMBL16401218 | 0.88 | PPARA (0.51) | NAAAPPARAFAAHIL6STACE | |
| SCHEMBL16401217 | 0.88 | PPARA (0.51) | NAAAPPARAFAAHIL6STACE | |
| SCHEMBL27101415 | 0.87 | PPARA (0.47) | NAAAPPARAFAAHIL6STACE | |
| SCHEMBL26181174 | 0.87 | PPARA (0.47) | NAAAPPARAFAAHIL6STACE | |
| SCHEMBL27101416 | 0.87 | PPARA (0.47) | NAAAPPARAFAAHIL6STACE | |
| SCHEMBL24252139 | 0.87 | PPARA (0.47) | NAAAPPARAFAAHIL6STIDH1 | |
| SCHEMBL16904002 | 0.86 | PPARA (0.47) | NAAAPPARAFAAHIL6STACE |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230364272-A1 | THERANOSTIC COMPOUNDS | UNIVERSITY OF CAPE TOWN (ZA) | 2023-11-16 | — | — | US | disclosed |
| US-20230364272-A1 | THERANOSTIC COMPOUNDS | UNIVERSITY OF CAPE TOWN (ZA) | 2023-11-16 | — | — | US | disclosed |
| WO-2022034544-A1 | THERANOSTIC COMPOUNDS | NRF ITHEMBA LABS (ZA) | 2022-02-17 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230364272-A1 | THERANOSTIC COMPOUNDS | MMP12, TIMP3, CTSZ | NAAA 79/4885PPARA 3187/4885FAAH 770/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.