Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 6/20 | 0.40 |
| ▸ | NPC1 | O15118 | 3/20 | 0.40 |
| ▸ | MAPT | P10636 | 3/20 | 0.40 |
| ▸ | MEN1 | O00255 | 3/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.40 |
| ▸ | RAB9A | P51151 | 2/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 4/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
| ▸ | PPARA | Q07869 | 1/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
| ▸ | EPAS1 | Q99814 | 2/20 | 0.37 |
| ▸ | SLC6A2 | P23975 | 3/20 | 0.36 |
| ▸ | SLC6A4 | P31645 | 3/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.36 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10872384 | 0.80 | L3MBTL1 (0.49) | L3MBTL1SMN1; SMN2NPC1MAPTMEN1 | |
| SCHEMBL30467694 | 0.77 | L3MBTL1 (0.47) | L3MBTL1SMN1; SMN2NPC1MAPTMEN1 | |
| SCHEMBL24253085 | 0.77 | L3MBTL1 (0.47) | L3MBTL1SMN1; SMN2NPC1MAPTMEN1 | |
| SCHEMBL24252932 | 0.77 | L3MBTL1 (0.47) | L3MBTL1SMN1; SMN2NPC1MAPTMEN1 | |
| SCHEMBL30452866 | 0.77 | L3MBTL1 (0.47) | L3MBTL1SMN1; SMN2NPC1MAPTMEN1 | |
| SCHEMBL24252446 | 0.76 | L3MBTL1 (0.46) | L3MBTL1SMN1; SMN2NPC1MAPTMEN1 | |
| SCHEMBL30467695 | 0.76 | L3MBTL1 (0.46) | L3MBTL1SMN1; SMN2NPC1MAPTMEN1 | |
| SCHEMBL30467654 | 0.74 | L3MBTL1 (0.44) | L3MBTL1SMN1; SMN2NPC1MAPTMEN1 | |
| SCHEMBL929274 | 0.72 | ALDH1A1 (0.52) | L3MBTL1SMN1; SMN2NPC1MAPTMEN1 | |
| SCHEMBL29958505 | 0.72 | ALDH1A1 (0.52) | L3MBTL1SMN1; SMN2NPC1MAPTMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11814404-B2 | Inhibitors of complement factors and uses thereof | ANNEXON, INC. (US) | 2023-11-14 | — | — | US | disclosed |
| US-20220048930-A1 | INHIBITORS OF COMPLEMENT FACTORS AND USES THEREOF | ANNEXON, INC. | 2022-02-17 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20220048930-A1 | INHIBITORS OF COMPLEMENT FACTORS AND USES THEREOF | CFB, CFH, C9 | L3MBTL1 4785/4885SMN1; SMN2 782/4885NPC1 460/4885 |
| US-11814404-B2 | Inhibitors of complement factors and uses thereof | CFB, CFH, C9 | L3MBTL1 4785/4885SMN1; SMN2 782/4885NPC1 460/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.