Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.47 |
| ▸ | EPAS1 | Q99814 | 3/20 | 0.43 |
| ▸ | PPARA | Q07869 | 1/20 | 0.39 |
| ▸ | GAA | P10253 | 2/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.38 |
| ▸ | MEN1 | O00255 | 3/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.38 |
| ▸ | NPC1 | O15118 | 2/20 | 0.38 |
| ▸ | MAPT | P10636 | 2/20 | 0.38 |
| ▸ | RAB9A | P51151 | 2/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.38 |
| ▸ | SLC6A2 | P23975 | 3/20 | 0.38 |
| ▸ | SLC6A4 | P31645 | 3/20 | 0.38 |
| ▸ | LMNA | P02545 | 3/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.38 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.37 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.37 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24252932 | 1.00 | L3MBTL1 (0.47) | L3MBTL1EPAS1PPARAGAASMN1; SMN2 | |
| SCHEMBL10872384 | 0.85 | L3MBTL1 (0.49) | L3MBTL1EPAS1PPARAGAASMN1; SMN2 | |
| SCHEMBL30467694 | 0.81 | L3MBTL1 (0.47) | L3MBTL1EPAS1PPARAGAASMN1; SMN2 | |
| SCHEMBL24253085 | 0.81 | L3MBTL1 (0.47) | L3MBTL1EPAS1PPARAGAASMN1; SMN2 | |
| SCHEMBL30467695 | 0.80 | L3MBTL1 (0.46) | L3MBTL1EPAS1PPARAGAASMN1; SMN2 | |
| SCHEMBL24252446 | 0.80 | L3MBTL1 (0.46) | L3MBTL1EPAS1PPARAGAASMN1; SMN2 | |
| SCHEMBL30467654 | 0.79 | L3MBTL1 (0.44) | L3MBTL1EPAS1PPARAGAASMN1; SMN2 | |
| SCHEMBL24252954 | 0.77 | L3MBTL1 (0.42) | L3MBTL1EPAS1PPARAGAASMN1; SMN2 | |
| SCHEMBL1369354 | 0.76 | PPARA (0.56) | PPARAGAASMN1; SMN2MEN1KMT2A | |
| SCHEMBL929274 | 0.74 | ALDH1A1 (0.52) | L3MBTL1SMN1; SMN2MEN1KMT2ANPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116947903-A | Inhibitors of complement factors and uses thereof | 安尼艾克松股份有限公司 | 2023-10-27 | — | — | CN | disclosed |
| CN-116261564-A | Inhibitors of complement factors and uses thereof | 安尼艾克松股份有限公司 | 2023-06-13 | — | — | CN | disclosed |