Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PIK3CG | P48736 | 1/20 | 0.34 |
| ▸ | EGFR | P00533 | 9/20 | 0.33 |
| ▸ | IMPDH2 | P12268 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10077013 | 0.80 | EGFR (0.38) | EGFR | |
| SCHEMBL29656626 | 0.80 | PIK3CG (0.36) | PIK3CGEGFR | |
| SCHEMBL25064814 | 0.77 | HPGD (0.40) | PIK3CGEGFRIMPDH2 | |
| SCHEMBL24868660 | 0.77 | PIK3CG (0.34) | PIK3CGEGFR | |
| SCHEMBL24248632 | 0.77 | PIK3CG (0.32) | PIK3CGEGFR | |
| SCHEMBL25092245 | 0.77 | AR (0.32) | PIK3CGEGFR | |
| SCHEMBL24253697 | 0.77 | PIK3CG (0.32) | PIK3CGEGFR | |
| SCHEMBL353198 | 0.73 | HCAR2 (0.35) | PIK3CG | |
| SCHEMBL11385198 | 0.69 | CCR1 (0.50) | EGFRIMPDH2 | |
| SCHEMBL29656681 | 0.69 | PIK3CG (0.40) | PIK3CGEGFR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230027684-A1 | METHODS AND COMPOSITIONS FOR MODULATING SPLICING | SKYHAWK THERAPEUTICS, INC. | 2023-01-26 | — | — | US | disclosed |
| US-20220048890-A1 | METHODS AND COMPOSITIONS FOR MODULATING SPLICING | SKYHAWK THERAPEUTICS, INC. | 2022-02-17 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20220048890-A1 | METHODS AND COMPOSITIONS FOR MODULATING SPLICING | RBM17, SF3B1, SF3B5 | PIK3CG 2230/4885EGFR 4824/4885IMPDH2 2857/4885 |
| US-20230027684-A1 | METHODS AND COMPOSITIONS FOR MODULATING SPLICING | RBM17, SF3B1, SF3B5 | PIK3CG 2230/4885EGFR 4824/4885IMPDH2 2857/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.