Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NQO2 | P16083 | 1/20 | 0.45 |
| ▸ | EGFR | P00533 | 1/20 | 0.43 |
| ▸ | MIF | P14174 | 1/20 | 0.41 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.41 |
| ▸ | KCNQ4 | P56696 | 3/20 | 0.40 |
| ▸ | KCNQ5 | Q9NR82 | 3/20 | 0.40 |
| ▸ | CNR2 | P34972 | 1/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.40 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.40 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.40 |
| ▸ | TNIK | Q9UKE5 | 1/20 | 0.39 |
| ▸ | CYP17A1 | P05093 | 2/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | CTSL | P07711 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17164920 | 0.85 | EGFR (0.49) | NQO2EGFRMIFKCNQ4KCNQ5 | |
| SCHEMBL24362149 | 0.84 | HPGD (0.47) | NQO2MIFRXFP1KCNQ4KCNQ5 | |
| SCHEMBL29618957 | 0.84 | HPGD (0.47) | NQO2MIFRXFP1KCNQ4KCNQ5 | |
| SCHEMBL21442757 | 0.84 | KCNQ4 (0.49) | RXFP1KCNQ4KCNQ5CNR2CYP1A2 | |
| SCHEMBL21734883 | 0.84 | IDO1 (0.44) | CYP2C9 | |
| SCHEMBL23093365 | 0.84 | KCNQ4 (0.41) | RXFP1KCNQ4KCNQ5CNR2CYP1A2 | |
| SCHEMBL12521472 | 0.84 | MAPK1 (0.48) | KCNQ4KCNQ5CNR2SMN1; SMN2 | |
| SCHEMBL24254051 | 0.82 | ALDH1A1 (0.46) | SMN1; SMN2 | |
| SCHEMBL29958958 | 0.81 | SMN1; SMN2 (0.47) | NQO2MIFRXFP1SMN1; SMN2POLB | |
| SCHEMBL2770751 | 0.81 | SMN1; SMN2 (0.47) | NQO2MIFRXFP1SMN1; SMN2POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022034587-A1 | Traf2- AND Nck-INTERACTING KINASE (TNIK) INHIBITORS AND USES THEREOF | TNIK THERAPEUTICS LTD (IL) | 2022-02-17 | — | — | WO | disclosed |