Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.44 |
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.42 |
| ▸ | F10 | P00742 | 1/20 | 0.42 |
| ▸ | TAS1R3 | Q7RTX0 | 1/20 | 0.42 |
| ▸ | TAS1R1 | Q7RTX1 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | LPAR1 | Q92633 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2156670 | 0.88 | AKR1C3 (0.48) | ALDH1A1KMT2AMEN1NR1I2F10 | |
| SCHEMBL7962276 | 0.86 | AKR1C3 (0.41) | ALDH1A1KMT2AMEN1NR1I2TAS1R3 | |
| SCHEMBL8762406 | 0.85 | ALDH1A1 (0.41) | ALDH1A1KMT2AMEN1NR1I2F10 | |
| SCHEMBL8502442 | 0.85 | MAPT (0.46) | ALDH1A1KMT2AMEN1NR1I2F10 | |
| SCHEMBL8762255 | 0.85 | TAS1R3 (0.44) | ALDH1A1KMT2AMEN1NR1I2F10 | |
| SCHEMBL3225589 | 0.84 | NR1I2 (0.41) | ALDH1A1KMT2AMEN1NR1I2F10 | |
| SCHEMBL8761832 | 0.84 | TAS1R3 (0.43) | ALDH1A1KMT2AMEN1NR1I2TAS1R3 | |
| SCHEMBL8924801 | 0.83 | MTNR1A (0.43) | ALDH1A1NR1I2SMN1; SMN2MAPT | |
| SCHEMBL8085605 | 0.82 | ALDH1A1 (0.42) | ALDH1A1KMT2ATAS1R3TAS1R1MAPT | |
| SCHEMBL8505209 | 0.82 | MTNR1A (0.39) | ALDH1A1KMT2AMEN1NR1I2F10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022034587-A1 | Traf2- AND Nck-INTERACTING KINASE (TNIK) INHIBITORS AND USES THEREOF | TNIK THERAPEUTICS LTD (IL) | 2022-02-17 | — | — | WO | disclosed |