⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29517242 | 1.00 | — | — | |
| Hydrochloric Acid SCHEMBL31416539 | 0.97 | TRPA1 (0.43) | — | |
| Hydrochloric Acid SCHEMBL2251205 | 0.97 | TRPA1 (0.43) | — | |
| SCHEMBL6508302 | 0.81 | PLAU (0.41) | — | |
| SCHEMBL6369936 | 0.81 | TRPA1 (0.39) | — | |
| SCHEMBL23246463 | 0.77 | CYP2B6 (0.34) | — | |
| SCHEMBL11639189 | 0.77 | TRPA1 (0.48) | — | |
| SCHEMBL11639187 | 0.77 | TRPA1 (0.48) | — | |
| SCHEMBL56690 | 0.75 | TRPA1 (0.42) | — | |
| SCHEMBL2771008 | 0.75 | TSHR (0.41) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1084 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4658655-A1 | CONDENSED HETEROCYCLIC COMPOUNDS AS INHIBITOR OF DIACYLGLYCEROL KINASES | Beone Medicines I GmbH (CH) | 2025-12-10 | — | — | EP | claimed |
| US-20250353858-A1 | CONDENSED HETEROCYCLIC COMPOUNDS AS INHIBITOR OF DIACYLGLYCEROL KINASES | BEONE MEDICINES I GMBH (CH) | 2025-11-20 | — | — | US | claimed |
| WO-2024160278-A1 | CONDENSED HETEROCYCLIC COMPOUNDS AS INHIBITOR OF DIACYLGLYCEROL KINASES | BEIGENE, LTD. (KY) | 2024-08-08 | — | — | WO | claimed |
| US-11833162-B2 | Macrocyclic derivatives, process for preparing same and pharmaceutical compositions containing same | LES LABORATOIRES SERVIER (FR) | 2023-12-05 | — | — | US | claimed |
| EP-3700911-B1 | NOVEL MACROCYCLIC DERIVATIVES, PROCESS FOR PREPARING SAME AND PHARMACEUTICAL COMPOSITIONS CONTAINING SAME | SERVIER LAB (FR) | 2023-09-06 | — | — | EP | claimed |
| CN-111511750-B | Macrocyclic derivatives, process for their preparation and pharmaceutical compositions containing them | 法国施维雅药厂 | 2023-06-13 | — | — | CN | claimed |
| CN-110627706-B | 2- (4-methylbenzyl) -1H-isoindole-1,3-diketone derivative and synthetic method thereof | 郑州手性药物研究院有限公司 | 2023-02-10 | — | — | CN | claimed |
| CN-110483439-B | Method for synthesizing 6-aminomethyl-1, 1-dioxo-1, 2-benzothiazole-3-one | 郑州手性药物研究院有限公司 | 2022-12-30 | — | — | CN | claimed |
| CN-110483497-B | 6-aminomethyl-1, 1-dioxo-1, 2-benzothiazol-3-one intermediate and synthetic method thereof | 郑州手性药物研究院有限公司 | 2022-12-30 | — | — | CN | claimed |
| EP-3980126-A1 | BENZO[H][1,6] NAPHTHYRIDIN-2(1H)-ONES AS BMX INHIBITORS, FOR USE AGAINST CANCER | Instituto de Medicina Molecular João Lobo Antunes (PT) | 2022-04-13 | — | — | EP | claimed |
| US-20060030701-A1 | Hydrophilizable and hydrophilic cyanine dyes | SILVERBROOK RESEARCH PTY LTD | 2006-02-09 | — | — | US | claimed |
| WO-2005079798-A1 | PYRIMIDINE DERIVATIVES AND USE THEREOF AS AGRICULTURAL AND HORTICULTURAL FUNGICIDES | BAYER CROPSCIENCE AG (DE) | 2005-09-01 | — | — | WO | claimed |
| US-6872839-B1 | Benzofuran-2-one | CIBASPECIALTY CHEMICALS CORP. (US) | 2005-03-29 | — | — | US | claimed |
| US-20040087798-A1 | Novel amide compounds | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 2004-05-06 | — | — | US | claimed |
| EP-1264820-A1 | NOVEL AMIDE COMPOUNDS | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 2002-12-11 | — | — | EP | claimed |
| EP-0528369-B1 | Cyclic imino derivatives, pharmaceutical compositions containing them and process for their preparation | BOEHRINGER INGELHEIM PHARMA (DE) | 1999-11-24 | — | — | EP | claimed |
| EP-0693059-A1 | PERHYDROISOINDOLE DERIVATIVES, PREPARATION THEREOF AND PHARMACEUTICAL COMPOSITIONS CONTAINING SAME | RHONE POULENC RORER SA (FR) | 1996-01-24 | — | — | EP | claimed |
| WO-1994022822-A1 | PERHYDROISOINDOLE DERIVATIVES, PREPARATION THEREOF AND PHARMACEUTICAL COMPOSITIONS CONTAINING SAME | RHONE-POULENC RORER S.A. (FR) | 1994-10-13 | — | — | WO | claimed |
| EP-0121326-B1 | ALKANEDIYL BRIDGED BENZIMIDAZOLO MONOMETHINE CYANINE DYES, PROCESSES FOR THEIR PREPARATION, AND PHOTOGRAPHIC EMULSIONS AND ELEMENTS CONTAINING SUCH DYES | EASTMAN KODAK COMPANY (a New Jersey corporation) (US) | 1989-05-17 | — | — | EP | claimed |
| EP-0023569-B1 | DERIVATIVES OF CARBOXYLIC ACIDS, THEIR PREPARATION AND MEDICAMENTS CONTAINING THEM | Dr. Karl Thomae GmbH (DE) | 1983-06-22 | — | — | EP | claimed |