SCHEMBL6508302

SCHEMBL6508302

C1=NCc2ccccc2-c2ccccc21

nearest known ligand 0.41

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
PLAU P00749 1/20 0.41
TSHR P16473 1/20 0.41
TRPA1 O75762 1/20 0.35
CES1 P23141 2/20 0.32
MAOA P21397 2/20 0.32
LMNA P02545 2/20 0.31
NOS3 P29474 1/20 0.31
NOS2 P35228 1/20 0.31
KDM4E B2RXH2 1/20 0.31
NPC1 O15118 1/20 0.31
ALDH1A1 P00352 1/20 0.31
MAPT P10636 1/20 0.31
HPGD P15428 1/20 0.31
RAB9A P51151 1/20 0.31
SMN1; SMN2 Q16637 1/20 0.31
POLB P06746 1/20 0.31
MAOB P27338 1/20 0.30
BCHE P06276 1/20 0.30
PTGS2 P35354 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29517242 0.81
SCHEMBL242542 0.81
Hydrochloric Acid SCHEMBL31416539 0.79 TRPA1 (0.43) PLAUTSHRTRPA1MAOB
Hydrochloric Acid SCHEMBL2251205 0.79 TRPA1 (0.43) PLAUTSHRTRPA1MAOB
SCHEMBL11179003 0.79 PLAU (0.35) PLAU
SCHEMBL10846631 0.78 PLAU (0.41) PLAUTSHRCES1MAOALMNA
SCHEMBL10846638 0.74
SCHEMBL691140 0.74 MAOA (0.41) PLAUTSHRCES1MAOAALDH1A1
SCHEMBL691141 0.74 MEN1 (0.35) CES1MAOALMNAKDM4ENPC1
SCHEMBL11680792 0.72 PIM1 (0.53) PLAUTSHRLMNAKDM4EALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2423214-A1 Light emitting materials for Electronics Solvay SA (BE) 2012-02-29 EP disclosed
WO-2012019948-A1 LIGHT EMITTING MATERIALS FOR ELECTRONICS SOLVAY SA (BE) 2012-02-16 WO disclosed
WO-2005056543-A2 PROCESS FOR USE IN THE PREPARATION OF OXIRANES FROM ALKENES, AND CATALYSTS FOR USE THEREIN AVECIA PHARMACEUTICALS LIMITED (GB) 2005-06-23 WO disclosed