Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | F2 | P00734 | 3/20 | 0.53 |
| ▸ | SMN1; SMN2 | Q16637 | 9/20 | 0.50 |
| ▸ | HPGD | P15428 | 5/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.48 |
| ▸ | TSHR | P16473 | 2/20 | 0.48 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.48 |
| ▸ | RAB9A | P51151 | 6/20 | 0.44 |
| ▸ | NPC1 | O15118 | 5/20 | 0.44 |
| ▸ | MAPT | P10636 | 2/20 | 0.44 |
| ▸ | PKM | P14618 | 1/20 | 0.44 |
| ▸ | LDHA | P00338 | 1/20 | 0.44 |
| ▸ | NFKB1 | P19838 | 2/20 | 0.43 |
| ▸ | NFKB2 | Q00653 | 2/20 | 0.43 |
| ▸ | RELA | Q04206 | 2/20 | 0.43 |
| ▸ | MEN1 | O00255 | 2/20 | 0.43 |
| ▸ | GAA | P10253 | 1/20 | 0.43 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.42 |
| ▸ | STAT1 | P42224 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9423275 | 0.81 | SMN1; SMN2 (0.49) | SMN1; SMN2HPGDKDM4EKMT2AALDH1A1 | |
| SCHEMBL2551230 | 0.78 | KLK3 (0.52) | F2SMN1; SMN2HPGDKDM4EKMT2A | |
| SCHEMBL9127293 | 0.74 | SMN1; SMN2 (0.49) | SMN1; SMN2HPGDKDM4EKMT2AALDH1A1 | |
| Hydrochloric Acid SCHEMBL9122448 | 0.73 | SMN1; SMN2 (0.47) | SMN1; SMN2HPGDKDM4EKMT2AALDH1A1 | |
| SCHEMBL4066437 | 0.72 | ALDH1A1 (0.46) | SMN1; SMN2HPGDKDM4EKMT2AALDH1A1 | |
| SCHEMBL4714412 | 0.72 | SMN1; SMN2 (0.54) | SMN1; SMN2HPGDKDM4EKMT2AALDH1A1 | |
| SCHEMBL167998 | 0.71 | SMN1; SMN2 (0.56) | SMN1; SMN2HPGDKDM4EKMT2AALDH1A1 | |
| SCHEMBL12285131 | 0.70 | F2 (1.00) | F2SMN1; SMN2HPGDKDM4EKMT2A | |
| SCHEMBL27139096 | 0.69 | SMN1; SMN2 (0.62) | SMN1; SMN2KDM4EKMT2AALDH1A1TSHR | |
| SCHEMBL2567843 | 0.69 | KLK3 (0.67) | F2KMT2ATSHRMAPTKLK3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022036033-A2 | SOLID STATE FORMS OF AN ORGANIC COMPOUND | SERVIER PHARMACEUTICALS, LLC (US) | 2022-02-17 | — | — | WO | disclosed |