Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 12/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 8/20 | 0.45 |
| ▸ | RAB9A | P51151 | 8/20 | 0.45 |
| ▸ | MEN1 | O00255 | 7/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 7/20 | 0.45 |
| ▸ | TSHR | P16473 | 1/20 | 0.45 |
| ▸ | GFER | P55789 | 1/20 | 0.45 |
| ▸ | MAPT | P10636 | 6/20 | 0.44 |
| ▸ | LMNA | P02545 | 2/20 | 0.44 |
| ▸ | STAT3 | P40763 | 2/20 | 0.44 |
| ▸ | NPC1 | O15118 | 7/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.43 |
| ▸ | GAA | P10253 | 3/20 | 0.43 |
| ▸ | HPGD | P15428 | 2/20 | 0.43 |
| ▸ | NFKB1 | P19838 | 3/20 | 0.43 |
| ▸ | NFKB2 | Q00653 | 3/20 | 0.43 |
| ▸ | RELA | Q04206 | 3/20 | 0.43 |
| ▸ | HTT | P42858 | 2/20 | 0.43 |
| ▸ | STAT1 | P42224 | 1/20 | 0.43 |
| ▸ | LDHA | P00338 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL9122448 | 0.98 | SMN1; SMN2 (0.47) | SMN1; SMN2ALDH1A1RAB9AMEN1KMT2A | |
| Hydrochloric Acid SCHEMBL9124745 | 0.85 | SMN1; SMN2 (0.47) | SMN1; SMN2ALDH1A1RAB9AMEN1KMT2A | |
| SCHEMBL9423275 | 0.83 | SMN1; SMN2 (0.49) | SMN1; SMN2ALDH1A1RAB9AMEN1KMT2A | |
| SCHEMBL9121292 | 0.83 | MAPT (0.44) | SMN1; SMN2ALDH1A1RAB9AMAPTLMNA | |
| Hydrochloric Acid SCHEMBL9121751 | 0.82 | SMN1; SMN2 (0.48) | SMN1; SMN2ALDH1A1RAB9AMEN1KMT2A | |
| Hydrochloric Acid SCHEMBL9124785 | 0.82 | MEN1 (0.50) | SMN1; SMN2ALDH1A1RAB9AMEN1KMT2A | |
| Hydrochloric Acid SCHEMBL9121359 | 0.82 | SMN1; SMN2 (0.54) | SMN1; SMN2ALDH1A1RAB9AMEN1KMT2A | |
| Hydrochloric Acid SCHEMBL9122359 | 0.82 | MAPT (0.43) | SMN1; SMN2RAB9AMEN1KMT2AMAPT | |
| Hydrochloric Acid SCHEMBL9123482 | 0.82 | RAB9A (0.55) | SMN1; SMN2ALDH1A1RAB9AMEN1KMT2A | |
| Hydrochloric Acid SCHEMBL9124771 | 0.79 | NPC1 (0.49) | SMN1; SMN2ALDH1A1RAB9AMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5453514-A | Diabetes | YAMANOUCHI PHARMACEUTICAL CO., LTD. (JP) | 1995-09-26 | — | — | US | disclosed |