Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 11/20 | 0.49 |
| ▸ | KLK3 | P07288 | 2/20 | 0.48 |
| ▸ | LDHA | P00338 | 1/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.47 |
| ▸ | MEN1 | O00255 | 7/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 7/20 | 0.45 |
| ▸ | RAB9A | P51151 | 6/20 | 0.45 |
| ▸ | TSHR | P16473 | 1/20 | 0.45 |
| ▸ | GFER | P55789 | 1/20 | 0.45 |
| ▸ | MAPT | P10636 | 7/20 | 0.45 |
| ▸ | NPC1 | O15118 | 5/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.45 |
| ▸ | PKM | P14618 | 1/20 | 0.45 |
| ▸ | LMNA | P02545 | 2/20 | 0.44 |
| ▸ | GAA | P10253 | 2/20 | 0.44 |
| ▸ | HTT | P42858 | 2/20 | 0.44 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.44 |
| ▸ | STAT3 | P40763 | 1/20 | 0.44 |
| ▸ | HPGD | P15428 | 2/20 | 0.43 |
| ▸ | STAT1 | P42224 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2551230 | 0.83 | KLK3 (0.52) | SMN1; SMN2KLK3LDHAALDH1A1KMT2A | |
| SCHEMBL9423332 | 0.83 | LMNA (0.49) | SMN1; SMN2KLK3ALDH1A1MEN1KMT2A | |
| SCHEMBL9127293 | 0.83 | SMN1; SMN2 (0.49) | SMN1; SMN2KLK3LDHAALDH1A1MEN1 | |
| Hydrochloric Acid SCHEMBL9122448 | 0.81 | SMN1; SMN2 (0.47) | SMN1; SMN2KLK3LDHAALDH1A1MEN1 | |
| SCHEMBL24254552 | 0.81 | F2 (0.53) | SMN1; SMN2KLK3LDHAALDH1A1MEN1 | |
| SCHEMBL15131264 | 0.76 | GRM5 (0.44) | SMN1; SMN2ALDH1A1MEN1KMT2ARAB9A | |
| SCHEMBL2567843 | 0.76 | KLK3 (0.67) | KLK3KMT2ATSHRMAPT | |
| SCHEMBL9423191 | 0.74 | PTGS1 (0.56) | ALDH1A1MEN1KMT2AMAPTKDM4E | |
| SCHEMBL4066437 | 0.74 | ALDH1A1 (0.46) | SMN1; SMN2KLK3LDHAALDH1A1MEN1 | |
| SCHEMBL28319903 | 0.74 | SMN1; SMN2 (0.59) | SMN1; SMN2ALDH1A1MEN1KMT2ARAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5358947-A | Treating hypertension, congestive heart failure | AMERICAN CYANAMID COMPANY (US) | 1994-10-25 | — | — | US | disclosed |