Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | VCAM1 | P19320 | 16/20 | 0.54 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.47 |
| ▸ | MAPT | P10636 | 1/20 | 0.47 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2080483 | 0.81 | VCAM1 (0.51) | VCAM1ALDH1A1MAPTTDP1 | |
| SCHEMBL5861079 | 0.80 | VCAM1 (0.55) | VCAM1MAPTTDP1 | |
| SCHEMBL18657403 | 0.80 | PDE7A (0.60) | VCAM1MAPTTDP1 | |
| SCHEMBL30387572 | 0.80 | VCAM1 (0.55) | VCAM1MAPTTDP1 | |
| SCHEMBL27957717 | 0.79 | VCAM1 (0.50) | VCAM1ALDH1A1MAPTTDP1 | |
| SCHEMBL21573611 | 0.77 | VCAM1 (0.54) | VCAM1ALDH1A1MAPTTDP1 | |
| SCHEMBL5861086 | 0.77 | VCAM1 (0.51) | VCAM1TDP1 | |
| SCHEMBL19249972 | 0.77 | TDP1 (0.53) | VCAM1ALDH1A1MAPTTDP1 | |
| SCHEMBL23507204 | 0.75 | PDE7A (0.58) | VCAM1MAPTTDP1 | |
| SCHEMBL7973695 | 0.74 | MAPT (0.61) | VCAM1ALDH1A1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022035804-A1 | SUBSTITUTED 3-AMINO-4-METHYLBENZENESULFONAMIDES AS SMALL MOLECULE INHIBITORS OF UBIQUITIN-SPECIFIC PROTEASE 28 | DANA-FARBER CANCER INSTITUTE, INC. (US) | 2022-02-17 | — | — | WO | disclosed |