Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | VCAM1 | P19320 | 11/20 | 0.55 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.53 |
| ▸ | DTYMK | P23919 | 1/20 | 0.51 |
| ▸ | MEN1 | O00255 | 1/20 | 0.47 |
| ▸ | LMNA | P02545 | 1/20 | 0.47 |
| ▸ | GAA | P10253 | 1/20 | 0.47 |
| ▸ | MAPT | P10636 | 1/20 | 0.47 |
| ▸ | HTT | P42858 | 1/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.47 |
| ▸ | PDE7A | Q13946 | 1/20 | 0.47 |
| ▸ | TSHR | P16473 | 1/20 | 0.47 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.47 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.46 |
| ▸ | NPBWR1 | P48145 | 1/20 | 0.45 |
| ▸ | MCHR1 | Q99705 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30387572 | 1.00 | VCAM1 (0.55) | VCAM1TDP1DTYMKMEN1LMNA | |
| SCHEMBL18562670 | 0.90 | ALDH1A1 (0.50) | VCAM1TDP1DTYMKMEN1LMNA | |
| SCHEMBL18657403 | 0.88 | PDE7A (0.60) | VCAM1TDP1LMNAMAPTPDE7A | |
| SCHEMBL21573611 | 0.85 | VCAM1 (0.54) | VCAM1TDP1MEN1MAPTKMT2A | |
| SCHEMBL2080483 | 0.85 | VCAM1 (0.51) | VCAM1TDP1LMNAMAPTPDE7A | |
| SCHEMBL5861086 | 0.85 | VCAM1 (0.51) | VCAM1TDP1PDE7ATSHRMAPK1 | |
| SCHEMBL27957717 | 0.83 | VCAM1 (0.50) | VCAM1TDP1LMNAMAPTPDE7A | |
| SCHEMBL23507204 | 0.82 | PDE7A (0.58) | VCAM1TDP1MEN1LMNAMAPT | |
| SCHEMBL11574501 | 0.80 | PDE7A (0.56) | VCAM1TDP1MEN1LMNAGAA | |
| SCHEMBL24254563 | 0.80 | VCAM1 (0.54) | VCAM1TDP1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 18 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6989263-B1 | Method for identifying and using compounds that inactivate HIV-1 and other retroviruses by attacking highly conserved zinc fingers in the viral nucleocapsid protein | THE UNITED STATES OF AMERICA AS REPRESENTED BY THE SECRETARY OF THE DEPARTMENT OF HEALTH AND HUMAN SERVICES (US) | 2006-01-24 | — | — | US | claimed |
| EP-2793578-B1 | N-ARYLAMIDINE-SUBSTITUTED TRIFLUOROETHYLSULFIDE DERIVATIVES AS ACARICIDES AND INSECTICIDES | BAYER CROPSCIENCE AG (DE) | 2018-06-06 | — | — | EP | disclosed |
| US-9642363-B2 | N-arylamidine-substituted trifluoroethyl sulfide derivatives as acaricides and insecticides | BAYER CROPSCIENCE AG (DE) | 2017-05-09 | — | — | US | disclosed |
| US-9642363-B2 | N-arylamidine-substituted trifluoroethyl sulfide derivatives as acaricides and insecticides | BAYER CROPSCIENCE AG (DE) | 2017-05-09 | — | — | US | disclosed |
| US-20170057914-A1 | N-ARYLAMIDINE-SUBSTITUTED TRIFLUOROETHYL SULFIDE DERIVATIVES AS ACARICIDES AND INSECTICIDES | BAYER CROPSCIENCE AG | 2017-03-02 | — | — | US | disclosed |
| US-20170057914-A1 | N-ARYLAMIDINE-SUBSTITUTED TRIFLUOROETHYL SULFIDE DERIVATIVES AS ACARICIDES AND INSECTICIDES | BAYER CROPSCIENCE AG | 2017-03-02 | — | — | US | disclosed |
| US-9512128-B2 | Aryl sulfide derivatives and aryl sulfoxide derivatives as acaricides and insecticides | BAYER CROPSCIENCE AG (DE) | 2016-12-06 | — | — | US | disclosed |
| US-9512128-B2 | Aryl sulfide derivatives and aryl sulfoxide derivatives as acaricides and insecticides | BAYER CROPSCIENCE AG (DE) | 2016-12-06 | — | — | US | disclosed |
| US-20150344499-A1 | ARYL SULFIDE DERIVATIVES AND ARYL SULFOXIDE DERIVATIVES AS ACARICIDES AND INSECTICIDES | BAYER CROPSCIENCE AG (DE) | 2015-12-03 | — | — | US | disclosed |
| US-20150344499-A1 | ARYL SULFIDE DERIVATIVES AND ARYL SULFOXIDE DERIVATIVES AS ACARICIDES AND INSECTICIDES | BAYER CROPSCIENCE AG (DE) | 2015-12-03 | — | — | US | disclosed |
| US-20140315898-A1 | N-ARYLAMIDINE-SUBSTITUTED TRIFLUOROETHYL SULFIDE DERIVATIVES AS ACARICIDES AND INSECTICIDES | BAYER CROPSCIENCE AG (DE) | 2014-10-23 | — | — | US | disclosed |
| US-20140315898-A1 | N-ARYLAMIDINE-SUBSTITUTED TRIFLUOROETHYL SULFIDE DERIVATIVES AS ACARICIDES AND INSECTICIDES | BAYER CROPSCIENCE AG (DE) | 2014-10-23 | — | — | US | disclosed |
| WO-2014095979-A1 | ARYL SULFIDE DERIVATIVES AND ARYL SULFOXIDE DERIVATIVES AS ACARICIDES AND INSECTICIDES | BAYER CROPSCIENCE AG (DE) | 2014-06-26 | — | — | WO | disclosed |
| WO-2013092350-A1 | N-ARYLAMIDINE-SUBSTITUTED TRIFLUOROETHYL SULFIDE DERIVATIVES AS ACARICIDES AND INSECTICIDES | BAYER CROPSCIENCE AG (DE) | 2013-06-27 | — | — | WO | disclosed |
| US-6943268-B2 | Method for induction of L-selectin shedding | SCIENCE & TECHNOLOGY CORPORATION @ UNM (US) | 2005-09-13 | — | — | US | disclosed |
| US-20030092763-A1 | Method for induction of L-selectin shedding | SCIENCE & TECHNOLOGY CORPORATION @UNM | 2003-05-15 | — | — | US | disclosed |
| EP-0782632-B1 | A METHOD FOR IDENTIFYING AND USING COMPOUNDS THAT INACTIVATE HIV-1 AND OTHER RETROVIRUSES BY ATTACKING HIGHLY CONSERVED ZINC FINGERS IN THE VIRAL NUCLEOCAPSID PROTEIN | US GOV HEALTH & HUMAN SERV (US) | 2003-04-16 | — | — | EP | disclosed |
| US-6498189-B1 | SUPPRESSION OF INFLAMMATION AND OF LYMPH NODE ENTRY BY CALMODULIN ANTAGONISTS; CELL ASSOCIATED PROTEIN DISULFIDE ISOMERASE INHIBITORS; P-AMINOPHENYLARSINE OXIDES | UNIVERSITY OF NEW MEXICO | 2002-12-24 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20140315898-A1 | N-ARYLAMIDINE-SUBSTITUTED TRIFLUOROETHYL SULFIDE DERIVATIVES AS ACARICIDES AND INSECTICIDES | AFF4, ARSA, AFF1 | VCAM1 4880/4885TDP1 4309/4885DTYMK 4593/4885 |
| US-20170057914-A1 | N-ARYLAMIDINE-SUBSTITUTED TRIFLUOROETHYL SULFIDE DERIVATIVES AS ACARICIDES AND INSECTICIDES | AFF4, ARSA, AFF1 | VCAM1 4880/4885TDP1 4309/4885DTYMK 4593/4885 |
| US-20030092763-A1 | Method for induction of L-selectin shedding | PDIA5, PDIA4, PDIA6 | VCAM1 14/4885TDP1 3141/4885DTYMK 1785/4885 |
| US-20150344499-A1 | ARYL SULFIDE DERIVATIVES AND ARYL SULFOXIDE DERIVATIVES AS ACARICIDES AND INSECTICIDES | ARSA, SQOR, AHR | VCAM1 4694/4885TDP1 4188/4885DTYMK 4704/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.