Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 3/20 | 0.72 |
| ▸ | CES2 | O00748 | 1/20 | 0.64 |
| ▸ | CES1 | P23141 | 1/20 | 0.64 |
| ▸ | ALDH1A1 | P00352 | 8/20 | 0.56 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.55 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.55 |
| ▸ | MEN1 | O00255 | 2/20 | 0.55 |
| ▸ | GAA | P10253 | 2/20 | 0.55 |
| ▸ | NPC1 | O15118 | 2/20 | 0.55 |
| ▸ | RAB9A | P51151 | 2/20 | 0.55 |
| ▸ | POLB | P06746 | 1/20 | 0.55 |
| ▸ | CTDSP1 | Q9GZU7 | 1/20 | 0.55 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.55 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.53 |
| ▸ | RECQL | P46063 | 1/20 | 0.53 |
| ▸ | MAPT | P10636 | 3/20 | 0.51 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30270576 | 1.00 | TSHR (0.72) | TSHRCES2CES1ALDH1A1KMT2A | |
| Ammonia Solution, Strong SCHEMBL27639793 | 0.98 | TSHR (0.70) | TSHRCES2CES1ALDH1A1KMT2A | |
| SCHEMBL8109329 | 0.92 | VCAM1 (0.64) | TSHRCES2CES1ALDH1A1SMN1; SMN2 | |
| SCHEMBL844701 | 0.86 | TSHR (0.72) | TSHRALDH1A1KMT2ASMN1; SMN2MEN1 | |
| SCHEMBL17303445 | 0.85 | TSHR (0.77) | TSHRCES2CES1ALDH1A1KMT2A | |
| SCHEMBL177231 | 0.84 | TSHR (1.00) | TSHRCES2CES1ALDH1A1KMT2A | |
| SCHEMBL30668892 | 0.84 | TSHR (1.00) | TSHRCES2CES1ALDH1A1KMT2A | |
| SCHEMBL571521 | 0.84 | TSHR (0.74) | TSHRCES2CES1ALDH1A1KMT2A | |
| SCHEMBL30041934 | 0.84 | TSHR (0.74) | TSHRCES2CES1ALDH1A1KMT2A | |
| SCHEMBL29492133 | 0.83 | CASP6 (0.69) | TSHRALDH1A1CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 365 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116178203-B | Polyimide containing amide bond and benzonorbornane structure and preparation method thereof | 南昌大学 | 2025-02-14 | — | — | CN | claimed |
| CN-119269665-A | Method for detecting menthol content based on rapid and catalyst-free pre-column derivative liquid chromatography | 广东超聚和生物科技有限公司 | 2025-01-07 | — | — | CN | claimed |
| CN-116178203-A | Polyimide containing amide bond and benzonorbornane structure and preparation method thereof | 南昌大学 | 2023-05-30 | — | — | CN | claimed |
| CN-112250796-A | Preparation method of BX/SGPS nitro-p-methyl benzoate-g-AM/MA | 桂林理工大学 | 2021-01-22 | — | — | CN | claimed |
| CN-112175141-A | Synthesis method of active cross-linked BX/SGPS nitro-p-methyl benzoate-g-AM | 桂林理工大学 | 2021-01-05 | — | — | CN | claimed |
| CN-112175140-A | Synthesis method of active BX/SGPS quaternary graft copolymerization derivative | 桂林理工大学 | 2021-01-05 | — | — | CN | claimed |
| CN-102267934-B | Method for preparing 6-carbomethoxy indolone | KINGCHEM DALIAN PHARMASCIENCE CO LTD | 2013-04-17 | — | — | CN | claimed |
| CN-102267934-A | Method for preparing 6-carbomethoxy indolone | — | 2011-12-07 | — | — | CN | claimed |
| CN-122036689-A | Nilotinib preparation method of nylon | 苏州特瑞药业股份有限公司 | 2026-05-15 | — | — | CN | disclosed |
| EP-4630423-A1 | COMPOUNDS AND COMPOSITIONS AS C-KIT KINASE INHIBITORS | Third Harmonic Bio, Inc. (US) | 2025-10-15 | — | — | EP | disclosed |
| US-20250154140-A1 | ISOQUINOLINE DERIVATIVES AS INHIBITORS OF BAX AND/OR BAK, COMPOSITIONS AND USES THEREOF | Sunnybrook Research Institute (CA) | 2025-05-15 | — | — | US | disclosed |
| CN-116178203-B | Polyimide containing amide bond and benzonorbornane structure and preparation method thereof | 南昌大学 | 2025-02-14 | — | — | CN | disclosed |
| CN-119431296-A | Alpha-MG xanthone-based NO donor compound, synthesis method and application | 北京立时达药业有限公司 | 2025-02-14 | — | — | CN | disclosed |
| CN-119269665-A | Method for detecting menthol content based on rapid and catalyst-free pre-column derivative liquid chromatography | 广东超聚和生物科技有限公司 | 2025-01-07 | — | — | CN | disclosed |
| US-4120891-A | COMPLEMENT INHIBITORS | AMERICAN CYANAMID COMPANY (US) | 1978-10-17 | — | — | US | disclosed |
| US-4103028-A | SUBSTITUTED HYDROXY NAPHTHALENEDISULFONIC ACIDS | AMERICAN CYANAMID COMPANY (US) | 1978-07-25 | — | — | US | disclosed |
| US-4087548-A | NAPHTHALENE TRISULFONIC ACIDS | AMERICAN CYANAMID COMPANY (US) | 1978-05-02 | — | — | US | disclosed |
| US-4052444-A | DIAZO COUPLERS FOR MONOAZO DYES | HOECHST AKTIENGESELLSCHAFT (DT) | 1977-10-04 | — | — | US | disclosed |
| US-4046805-A | Substituted-hydroxy-naphthalenedisulfonic acid compounds | AMERICAN CYANAMID COMPANY (US) | 1977-09-06 | — | — | US | disclosed |
| US-3971741-A | DISPERSION PIGMENTS | BAYER AKTIENGESELLSCHAFT (DT) | 1976-07-27 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20250154140-A1 | ISOQUINOLINE DERIVATIVES AS INHIBITORS OF BAX AND/OR BAK, COMPOSITIONS AND USES THEREOF | BAK1, BAX, BCL2 | TSHR 4782/4885CES2 4463/4885CES1 4302/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.